Evidence map›Paper›PMID 38424180›Full record

ArticleScientific reports2024

MRI-based central sarcopenia negatively impacts the therapeutic effectiveness of single-segment lumbar fusion surgery in the elderly.

Kai Sun, Haoran Zhu, Bo Huang, Jun Li, Genjiu Liu, Genlong Jiao, Guoliang Chen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Sarcopenia, paraspinal muscle degeneration, and bone quality as prognostic factors for adjacent segment degeneration or disease after lumbar fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kai Sun *Department of Orthopedic Surgery, Jiujiang University Affiliated Hospital, Jiujiang, 332006, China.
Haoran Zhu *Department of Orthopedic Surgery, The Fifth Affiliated Hospital of Jinan University (Heyuan Shenhe People's Hospital), Heyuan, 517400, China.
Bo Huang *Department of Orthopedic Surgery, Jiujiang University Affiliated Hospital, Jiujiang, 332006, China.
Jun LiDepartment of Orthopedic Surgery, Jiujiang University Affiliated Hospital, Jiujiang, 332006, China.
Genjiu LiuDongguan Key Laboratory of Central Nervous System Injury and Repair / Department of Orthopedic Surgery, The Sixth Affiliated Hospital of Jinan University (Dongguan Eastern Central Hospital), Dongguan, 523573, China. dglgj@sohu.com.
Genlong JiaoDongguan Key Laboratory of Central Nervous System Injury and Repair / Department of Orthopedic Surgery, The Sixth Affiliated Hospital of Jinan University (Dongguan Eastern Central Hospital), Dongguan, 523573, China. tjglong@jnu.edu.cn.
Guoliang ChenDepartment of Orthopedic Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. chenguoliang@jnu.edu.cn.
Jiujiang University · CNDongguan People’s Hospital · CNFirst Affiliated Hospital of Jinan University · CNJinan University · CN

Funding

Dongguan Science and Technology of Social Development Program 20231800939902Fundamental Research Funds for the Central Universities 21623310Guangdong Basic and Applied Basic Research Foundation 2022A1515140171Guangzhou Municipal Science and Technology Bureau SL2023A04J01534Jiangxi Province Health Science and Technology Program 202311519Medical Joint Fund of Jinan University YXJC2022011
6 · The paper itself

Abstract

Central sarcopenia is associated with the prognosis of various orthopedic surgeries in the elderly. This study aims to investigate its impact on the outcomes of single-segment lumbar fusion surgery in elderly patients. Retrospective analysis was conducted on 314 patients aged 60 to 80 who underwent single-segment posterior lumbar fusion surgery due to degenerative lumbar diseases. Patients were categorized into high psoas and L4 vertebral index (PLVI) and low PLVI groups according to the MRI-measured PLVI for central sarcopenia. Basic patient data, surgery-related parameters, functional assessments at preoperative and postoperative 3, 6, and 12 months, and X-ray-based fusion status were compared. The basic data of the two groups showed no significant differences. Parameters including the operative segment, preoperative hemoglobin levels, surgical duration, and intraoperative blood loss exhibited no significant variances. However, notable differences were observed in postoperative initial hemoglobin levels, transfusion requirements, and length of hospital stay between the two groups. During the postoperative follow-ups at 3, 6, and 12 months, the VAS scores for lower back pain and ODI scores in the lower PLVI group were significantly higher compared to the high PLVI group. Additionally, the EuroQoL 5D scores were notably lower in the low PLVI group. There were no significant differences between the groups in terms of leg pain VAS scores at each time point and the fusion status at 12 months postoperatively. MRI-based central sarcopenia has a negative impact on the therapeutic effectiveness following single-segment lumbar fusion surgery in elderly patients.

Indexed as

SarcopeniaSpinal FusionAgedHemoglobinsHumansLumbar VertebraeMagnetic Resonance ImagingRetrospective StudiesTreatment OutcomeHemoglobinsCentral sarcopeniaElderlyLumbar fusionPsoas and L4 vertebral index

Identifiers

PMID38424180
PMCPMC10904385
OpenAlexW4392282721

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.