Evidence map›Paper›PMID 38424097›Full record

ArticleScientific data2024

Brain tumor segmentation using synthetic MR images - A comparison of GANs and diffusion models.

Muhammad Usman Akbar, Måns Larsson, Ida Blystad, Anders Eklund

Abstract read
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad Usman AkbarDepartment of Biomedical Engineering, Linköping University, Linköping, Sweden.
Måns LarssonEigenvision, Malmö, Sweden.
Ida BlystadCenter for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.ORCID 0000-0002-8857-5698
Anders EklundDepartment of Biomedical Engineering, Linköping University, Linköping, Sweden. anders.eklund@liu.se.ORCID 0000-0001-7061-7995

Funding

VINNOVA (Swedish Governmental Agency for Innovation Systems) 2021-01954
6 · The paper itself

Abstract

Large annotated datasets are required for training deep learning models, but in medical imaging data sharing is often complicated due to ethics, anonymization and data protection legislation. Generative AI models, such as generative adversarial networks (GANs) and diffusion models, can today produce very realistic synthetic images, and can potentially facilitate data sharing. However, in order to share synthetic medical images it must first be demonstrated that they can be used for training different networks with acceptable performance. Here, we therefore comprehensively evaluate four GANs (progressive GAN, StyleGAN 1-3) and a diffusion model for the task of brain tumor segmentation (using two segmentation networks, U-Net and a Swin transformer). Our results show that segmentation networks trained on synthetic images reach Dice scores that are 80%-90% of Dice scores when training with real images, but that memorization of the training images can be a problem for diffusion models if the original dataset is too small. Our conclusion is that sharing synthetic medical images is a viable option to sharing real images, but that further work is required. The trained generative models and the generated synthetic images are shared on AIDA data hub.

Indexed as

Brain NeoplasmsDatasets as TopicHumansImage Processing, Computer-AssistedInformation Dissemination

Identifiers

PMID38424097
PMCPMC10904731

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.