Evidence map›Paper›PMID 38423777›Full record

ArticleBMJ open2024

Air pollution and human health: a phenome-wide association study.

Emilie Rune Hegelund, Amar J Mehta, Zorana J Andersen, Youn-Hee Lim, Steffen Loft, Bert Brunekreef, Gerard Hoek, Kees de Hoogh, Laust Hvas Mortensen

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Is Pollution the Primary Driver of Infectious Syndemics?Pathogens (Basel, Switzerland) · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Emilie Rune HegelundStatistics Denmark, Copenhagen, Denmark ehe@dst.dk.ORCID 0000-0001-8677-7133
Amar J MehtaUniversity of Copenhagen, Copenhagen, Denmark.
Zorana J AndersenUniversity of Copenhagen, Copenhagen, Denmark.
Youn-Hee LimUniversity of Copenhagen, Copenhagen, Denmark.
Steffen LoftUniversity of Copenhagen, Copenhagen, Denmark.
Bert BrunekreefUtrecht University, Utrecht, the Netherlands.
Gerard HoekUtrecht University, Utrecht, the Netherlands.
Kees de HooghSwiss Tropical and Public Health Institute, Allschwil, Switzerland.
Laust Hvas MortensenStatistics Denmark, Copenhagen, Denmark.
University of Copenhagen · DKStatistics Denmark · DKUtrecht University · NLSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the associations of long-term exposure to air pollution with onset of all human health conditions.

designProspective phenome-wide association study.

settingDenmark.

participantsAll Danish residents aged ≥30 years on 1 January 2000 were included (N=3 323 612). After exclusion of individuals with missing geocoded residential addresses, 3 111 988 participants were available for the statistical analyses.

main outcome measureFirst registered diagnosis of every health condition according to the International Classification of Diseases, 10th revision, from 2000 to 2017.

resultsLong-term exposure to fine particulate matter (PM

conclusionsThe findings of this study suggest that air pollution has a more extensive impact on human health than previously known. However, as this study is the first of its kind to investigate the associations of long-term exposure to air pollution with onset of all human health conditions, further research is needed to replicate the study findings.

Indexed as

Air PollutantsAir PollutionDiabetes Mellitus, Type 2Environmental ExposureHumansNitrogen DioxideParticulate MatterProspective StudiesAir PollutantsNitrogen DioxideParticulate MatterEPIDEMIOLOGYObservational StudyPUBLIC HEALTHREGISTRIES

Identifiers

PMID38423777
PMCPMC10910582
OpenAlexW4392451285

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.