Observational studyThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2024
Post-transplant survival after normothermic regional perfusion versus direct procurement and perfusion in donation after circulatory determination of death in heart transplantation.
Observational study in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Reperfusion Strategies in Donation After Circulatory Death Heart Transplantation: An Up-to-Date Narrative Review.Journal of clinical medicine · 2026Review
- Recent perioperative challenges in anesthesia during expansion of heart transplantation.Journal of cardiothoracic surgery · 2026Review
- Heart transplantation graft survival following donation after circulatory death via thoracoabdominal normothermic regional perfusion.JHLT open · 2026Article
- Modernizing the national transplant database.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025Review
- Early and Mid-Term Results of Solid Organ Transplantation After Circulatory Death: A 4-Year Single Centre Experience.Medicina (Kaunas, Lithuania) · 2025Article
- Optimization of pretransplant amiodarone therapy to prevent primary graft dysfunction following heart transplantation.JHLT open · 2025Article
- Simultaneous Heart and Kidney Transplantation Using Circulatory Death Donors: Are Kidney Graft Outcomes Comparable With Brain Death Donors?Transplantation direct · 2025Article
- Early outcomes in heart transplantation using donation after circulatory death donors in patients bridged with durable left ventricular assist devices.The Journal of thoracic and cardiovascular surgery · 2025Article
- Brief hypothermic oxygenated perfusion provides cardioprotection in a pig model of donation after circulatory death.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
- Use of Normothermic Regional Perfusion in Circulatory Death Donors for Lung Transplantation in the United States.Clinical transplantation · 2025Article
- Differential Effects of Brain Death and Circulatory Death on Myocardial Integrity and Transplant Outcomes.Journal of surgery and research · 2025Article
- Heart Transplantation and Donation After Circulatory Death in Children. A Review of the Technological, Logistical and Ethical Framework.Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- The Rapidly Evolving Landscape of DCD Heart Transplantation.Current cardiology reports · 2024Review
- Heart transplantation from donation after circulatory death: a meta-analysis of national registries.Annals of cardiothoracic surgery · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundSince 2019, the annual transplantation rate of hearts donated following circulatory death (DCD) has increased significantly in the United States. The 2 major heart procurement techniques following circulatory death are direct procurement and perfusion (DPP) and normothermic regional perfusion (NRP). Post-transplant survival for heart recipients has not been compared between these 2 techniques.
methodsThis observational study uses data on adult heart transplants from donors after circulatory death from January 1, 2019 to December 31, 2021 in the Scientific Registry of Transplant Recipients. We identified comparable transplant cases across procurement types using propensity-score matching and measured the association between procurement technique and 1-year post-transplant survival using Kaplan-Meier and Cox proportional hazards model stratefied by matching pairs.
resultsAmong 318 DCD heart transplants, 216 (68%) were procured via DPP, and 102 (32%) via NRP. Among 22 transplant centers that accepted circulatory-death donors, 3 used NRP exclusively, and 5 used both procurement techniques. After propensity-score matching on recipient and donor factors, there was no significant difference in 1-year post-transplant survival (93.1% for NRP vs 91.1% for DPP, p = 0.79) between procurement techniques.
conclusionsNRP and DPP procurements are associated with similar 1-year post-transplant survival. If NRP is ethically permissible and improves outcomes for abdominal organs, it should be the preferred procurement technique for DCD hearts.
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