Evidence map›Paper›PMID 38423105›Full record

ArticleInternational journal of epidemiology2024

M-estimation for common epidemiological measures: introduction and applied examples.

Rachael K Ross, Paul N Zivich, Jeffrey S A Stringer, Stephen R Cole

Abstract read
In one paragraph

Article in International journal of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. The Rogan-Gladen estimator for outcome misclassification.American journal of epidemiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Five Facts About Influence Functions.Epidemiology (Cambridge, Mass.) · 2025
    Article
  7. A minimal nontrivial example of higher-order evidence.American journal of epidemiology · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rachael K RossDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.ORCID 0000-0002-2049-6918
Paul N ZivichInstitute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jeffrey S A StringerDepartment of Obstetrics and Gynecology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Stephen R ColeDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Training in Sexually Transmitted Infections and HIVT32AI007001 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SENA-SOBERANO, ARLENE C. · 1985 to 2025
$10.9M
Improved analysis of experiments and observational studies in HIVR01AI157758 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephen R Cole, Jessie Edwards · 2020 to 2026
$5.0M
Design and analysis advances to improve generalizability of clinical trials for treating opioid use disorderR01DA056407 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Kara Elizabeth Rudolph, Elizabeth A. Stuart · 2022 to 2026
$3.1M
Combining sources of information to improve HIV pre-exposure prophylaxisK01AI177102 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Paul Nicholas Zivich · 2023 to 2026
$545k
Gates Foundation INV-016221NIAID NIH HHS K01 AI177102NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI157758NIAID NIH HHS T32 AI007001NIDA NIH HHS R01 DA056407NIH HHS 5P30AI050410
6 · The paper itself

Abstract

M-estimation is a statistical procedure that is particularly advantageous for some comon epidemiological analyses, including approaches to estimate an adjusted marginal risk contrast (i.e. inverse probability weighting and g-computation) and data fusion. In such settings, maximum likelihood variance estimates are not consistent. Thus, epidemiologists often resort to bootstrap to estimate the variance. In contrast, M-estimation allows for consistent variance estimates in these settings without requiring the computational complexity of the bootstrap. In this paper, we introduce M-estimation and provide four illustrative examples of implementation along with software code in multiple languages. M-estimation is a flexible and computationally efficient estimation procedure that is a powerful addition to the epidemiologist's toolbox.

Indexed as

EpidemiologistsLanguageComputer SimulationHumansModels, StatisticalProbabilitySoftwaredata fusionestimating equationslogistic regressionM-estimationstandardization

Identifiers

PMID38423105
PMCPMC10904145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.