Evidence map›Paper›PMID 38422478›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Machine Learning of Plasma Proteomics Classifies Diagnosis of Interstitial Lung Disease.

Yong Huang, Shwu-Fan Ma, Justin M Oldham, Ayodeji Adegunsoye, Daisy Zhu, Susan Murray, John S Kim, Catherine Bonham, Emma Strickland, Angela L Linderholm and 8 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Artificial intelligence in respiratory medicine: From diagnosis to treatment and future directions.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Pulmonary Fibrosis-Focusing on the Future: Aspen Lung Conference 2024 Summary.American journal of respiratory cell and molecular biology · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Proteomic Biomarkers of Survival in Non-Idiopathic Pulmonary Fibrosis Interstitial Lung Disease.American journal of respiratory and critical care medicine · 2025
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Yong HuangDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Shwu-Fan MaDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.ORCID 0000-0002-3058-9480
Justin M OldhamDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4957-8869
Ayodeji AdegunsoyeSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.
Daisy ZhuDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Susan MurrayDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
John S KimDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Catherine BonhamDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.ORCID 0000-0001-9132-4083
Emma StricklandDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Angela L LinderholmDivision of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis, Davis, California.
Cathryn T LeeSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.
Tessy PaulDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Hannah MannemDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.
Toby M MaherNational Heart and Lung Institute, Imperial College, London, United Kingdom.ORCID 0000-0001-7192-9149
Philip L MolyneauxNational Heart and Lung Institute, Imperial College, London, United Kingdom.ORCID 0000-0003-1301-8800
Mary E StrekSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.
Fernando J MartinezWeill Cornell Medical Center, New York, New York.
Imre NothDivision of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, Virginia.

Funding

RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
Architectural structure and regulation of TOLLIP in IPFR01HL130796 · NHLBI · UNIVERSITY OF VIRGINIA · PI NOTH, IMRE · 2016 to 2019
$3.1M
Proteomic Profiling of Idiopathic Pulmonary Fibrosis Progression TrajectoryR01HL169166 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2023 to 2026
$2.7M
Prognostic Biomarker Development in Progressive Fibrosing Interstitial Lung DiseaseR01HL166290 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2024 to 2026
$2.2M
1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyUG3HL145266 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J, NOTH, IMRE · 2019 to 2019
$977k
Elucidating the Genomic Determinants of Outcomes in Idiopathic Pulmonary FibrosisK23HL138190 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, JUSTIN M · 2017 to 2021
$914k
Role of polyunsaturated fatty acids in pulmonary fibrosisK23HL150301 · NHLBI · UNIVERSITY OF VIRGINIA · PI KIM, JOHN S · 2021 to 2025
$858k
Improving Pulmonary Fibrosis Classification with Genomics Informed Phenotypic ClustersK23HL146942 · NHLBI · UNIVERSITY OF CHICAGO · PI ADEGUNSOYE, AYODEJI · 2020 to 2024
$810k
NHLBI NIH HHS K23 HL138190NHLBI NIH HHS K23HL138190NHLBI NIH HHS K23 HL146942NHLBI NIH HHS K23HL146942NHLBI NIH HHS K23 HL150301NHLBI NIH HHS K23HL150301NHLBI NIH HHS R01 HL130796NHLBI NIH HHS R01HL130796NHLBI NIH HHS R01 HL166290NHLBI NIH HHS R01 HL169166NHLBI NIH HHS T32 HL007605NHLBI NIH HHS T32HL007605NHLBI NIH HHS UG3 HL145266NHLBI NIH HHS UG3HL145266
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung Diseases, InterstitialMachine LearningProteomicsAgedBiomarkersConnective Tissue DiseasesDiagnosis, DifferentialFemaleHumansIdiopathic Pulmonary FibrosisMaleMiddle AgedBiomarkersconnective tissue disease with ILDdifferential diagnosisidiopathic pulmonary fibrosismachine learning modelplasma proteomics

Identifiers

PMID38422478
PMCPMC11351805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.