Evidence map›Paper›PMID 38421972›Full record

ArticlePloS one2024

Breast hypoplasia markers among women who report insufficient milk production: A retrospective online survey.

Renee L Kam, Lisa H Amir, Meabh Cullinane, Jenny Ingram, Xia Li, Laurie A Nommsen-Rivers

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Renee L KamJudith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Bundoora, Victoria, Australia.ORCID 0000-0002-2547-2085
Lisa H AmirJudith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Bundoora, Victoria, Australia.
Meabh CullinaneJudith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Bundoora, Victoria, Australia.
Jenny IngramBristol Medical School, University of Bristol, Bristol, United Kingdom.
Xia LiDepartment of Mathematics and Statistics, La Trobe University, Bundoora, Victoria, Australia.
Laurie A Nommsen-RiversCollege of Allied Health Sciences, University of Cincinnati, Cincinnati, Ohio, United States of America.
La Trobe University · AURoyal Women's Hospital · AUUniversity of Bristol · GBUniversity of Cincinnati Medical Center · US

Funding

MOM2CHild Study: Leveraging systems biology toward discoveries in Maternal Obesity, Milk, and Translation To Child HealthR01HD109915 · NICHD · UNIVERSITY OF CINCINNATI · PI ARDYTHE L MORROW · 2022 to 2026
$3.9M
NICHD NIH HHS R01 HD109915
6 · The paper itself

Abstract

objectivesTo estimate the proportions of anatomical breast characteristics suggestive of breast hypoplasia among breastfeeding women self-reporting low milk supply. We also explored breast hypoplasia risk factors.

designOnline survey conducted between October 2021 and January 2022.

settingFive low milk supply Facebook groups.

participants487 women reporting low milk supply with their first child born ≥ 37 weeks gestation within 5 years of participation in this study, and residing in the USA, Australia or the UK. We present data on the primary outcome ('breast type') for 399 women. Women were excluded if the dyad was separated for more than 24 hours during the hospital stay, or if the mother reported removing milk less than 6 times per day from each breast on most days before being aware of having insufficient milk production. PRIMARY AND SECONDARY OUTCOME MEASURES: The proportions of proposed breast hypoplasia markers including atypical breast type, widely spaced breasts, breast asymmetry, stretch marks on the breast and lack of pregnancy breast growth. We also estimated the odds of having breast hypoplasia markers in at-risk groups compared to reference groups, adjusting for covariates.

resultsApproximately 68% reported at least one atypical breast (270/399; 95% CI: 62.9%, 72.1%). Around 47% reported widely spaced breasts (212/449; 95% CI: 42.7%, 52.7%), 72% a lack of pregnancy breast growth (322/449; 95% CI: 68.3%, 77.4%), and 76% stretch marks on the breast (191/250; 95% CI: 70.7%, 81.3%). Multiple logistic regression analyses identified being overweight during pubertal years as a risk factor for atypical breast type and lack of pregnancy breast growth.

conclusionsParticipants in low milk supply Facebook groups reported high rates of breast hypoplasia markers. Being overweight during adolescence was a risk factor for breast hypoplasia markers. These findings should be confirmed in well-conducted large cohort studies to determine the strongest combination of hypoplasia markers in predicting low supply.

Indexed as

MilkStriae DistensaeAdolescentAnimalsBreastBreast FeedingChildFemaleHumansMilk, HumanOverweightPregnancyRetrospective Studies

Identifiers

PMID38421972
PMCPMC10903845
OpenAlexW4392283901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.