Evidence map›Paper›PMID 38421945›Full record

ArticleMMWR. Morbidity and mortality weekly report2024

Interim Effectiveness of Updated 2023-2024 (Monovalent XBB.1.5) COVID-19 Vaccines Against COVID-19-Associated Emergency Department and Urgent Care Encounters and Hospitalization Among Immunocompetent Adults Aged ≥18 Years - VISION and IVY Networks, September 2023-January 2024.

Jennifer DeCuir, Amanda B Payne, Wesley H Self, Elizabeth A K Rowley, Kristin Dascomb, Malini B DeSilva, Stephanie A Irving, Shaun J Grannis, Toan C Ong, Nicola P Klein and 55 more

Open access · diamondAbstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
38.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

65 authors at 1 institution in 1 country.

Jennifer DeCuir
Amanda B Payne
Wesley H Self
Elizabeth A K Rowley
Kristin Dascomb
Malini B DeSilva
Stephanie A Irving
Shaun J Grannis
Toan C Ong
Nicola P Klein
Zachary A Weber
Sarah E Reese
Sarah W Ball
Michelle A Barron
Allison L Naleway
Brian E Dixon
Inih Essien
Daniel Bride
Karthik Natarajan
Bruce Fireman
Ami B Shah
Erica Okwuazi
Ryan Wiegand
Yuwei Zhu
Adam S Lauring
Emily T Martin
Manjusha Gaglani
Ithan D Peltan
Samuel M Brown
Adit A Ginde
Nicholas M Mohr
Kevin W Gibbs
David N Hager
Matthew Prekker
Amira Mohamed
Vasisht Srinivasan
Jay S Steingrub
Akram Khan
Laurence W Busse
Abhijit Duggal
Jennifer G Wilson
Steven Y Chang
Christopher Mallow
Jennie H Kwon
Matthew C Exline
Cristie Columbus
Ivana A Vaughn
Basmah Safdar
Jarrod M Mosier
Estelle S Harris
Jonathan D Casey
James D Chappell
Carlos G Grijalva
Sydney A Swan
Cassandra Johnson
Nathaniel M Lewis
Sascha Ellington
Katherine Adams
Mark W Tenforde
Clinton R Paden
Fatimah S Dawood
Katherine E Fleming-Dutra
Diya Surie
Ruth Link-Gelles
CDC COVID-19 Vaccine Effectiveness Collaborators
Intermountain Healthcare · US

Funding

Measuring and Learning from Care Variation in SepsisR35GM151147 · NIGMS · IHC HEALTH SERVICES, INC. · PI Ithan Daniel Peltan · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM151147
6 · The paper itself

Abstract

In September 2023, CDC's Advisory Committee on Immunization Practices recommended updated 2023-2024 (monovalent XBB.1.5) COVID-19 vaccination for all persons aged ≥6 months to prevent COVID-19, including severe disease. However, few estimates of updated vaccine effectiveness (VE) against medically attended illness are available. This analysis evaluated VE of an updated COVID-19 vaccine dose against COVID-19-associated emergency department (ED) or urgent care (UC) encounters and hospitalization among immunocompetent adults aged ≥18 years during September 2023-January 2024 using a test-negative, case-control design with data from two CDC VE networks. VE against COVID-19-associated ED/UC encounters was 51% (95% CI = 47%-54%) during the first 7-59 days after an updated dose and 39% (95% CI = 33%-45%) during the 60-119 days after an updated dose. VE estimates against COVID-19-associated hospitalization from two CDC VE networks were 52% (95% CI = 47%-57%) and 43% (95% CI = 27%-56%), with a median interval from updated dose of 42 and 47 days, respectively. Updated COVID-19 vaccine provided increased protection against COVID-19-associated ED/UC encounters and hospitalization among immunocompetent adults. These results support CDC recommendations for updated 2023-2024 COVID-19 vaccination. All persons aged ≥6 months should receive updated 2023-2024 COVID-19 vaccine.

Indexed as

COVID-19COVID-19 VaccinesAdolescentAdultAdvisory CommitteesEmergency Service, HospitalHospitalizationHumansCOVID-19 Vaccines

Identifiers

PMID38421945
PMCPMC10907041
OpenAlexW4392297152

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.