Evidence map›Paper›PMID 38421870›Full record

ArticleCell reports2024

Neural correlates of novelty detection in the primary auditory cortex of behaving monkeys.

Yumei Gong, Peirun Song, Xinyu Du, Yuying Zhai, Haoxuan Xu, Hangting Ye, Xuehui Bao, Qianyue Huang, Zhiyi Tu, Pei Chen and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
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  4. Hierarchical substrates of prediction in visual cortical spiking.bioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Yumei GongDepartment of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, Shanghai, China; Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Hangzhou Extremely Weak Magnetic Field Major Science and Technology, Infrastructure Research Institute, Hangzhou 310000, China; Interdisciplinary Institute of Neuroscience and Technology, College of Biomedical, Engineering, and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.
Peirun SongDepartment of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Xinyu DuDepartment of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Yuying ZhaiDepartment of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Haoxuan XuInterdisciplinary Institute of Neuroscience and Technology, College of Biomedical, Engineering, and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.
Hangting YeDepartment of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Xuehui BaoInterdisciplinary Institute of Neuroscience and Technology, College of Biomedical, Engineering, and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.
Qianyue HuangInterdisciplinary Institute of Neuroscience and Technology, College of Biomedical, Engineering, and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.
Zhiyi TuDepartment of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, Shanghai, China.
Pei ChenDepartment of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, Shanghai, China.
Xuan ZhaoDepartment of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, Shanghai, China.
David Pérez-GonzálezCognitive and Auditory Neuroscience Laboratory (Lab 1), Institute of Neuroscience of Castilla y León (INCYL), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Department of Basic Psychology, Psychobiology, and Methodology of Behavioral Sciences, Faculty of Psychology, University of Salamanca, Salamanca, Spain.
Manuel S MalmiercaCognitive and Auditory Neuroscience Laboratory (Lab 1), Institute of Neuroscience of Castilla y León (INCYL), University of Salamanca, Salamanca, Spain; Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain; Department of Cell Biology and Pathology, Faculty of Medicine, University of Salamanca, Salamanca, Spain. Electronic address: msm@usal.es.
Xiongjie YuDepartment of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, Shanghai, China; Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: yuxiongj@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neural mechanisms underlying novelty detection are not well understood, especially in relation to behavior. Here, we present single-unit responses from the primary auditory cortex (A1) from two monkeys trained to detect deviant tones amid repetitive ones. Results show that monkeys can detect deviant sounds, and there is a strong correlation between late neuronal responses (250-350 ms after deviant onset) and the monkeys' perceptual decisions. The magnitude and timing of both neuronal and behavioral responses are increased by larger frequency differences between the deviant and standard tones and by increasing the number of standard tones preceding the deviant. This suggests that A1 neurons encode novelty detection in behaving monkeys, influenced by stimulus relevance and expectations. This study provides evidence supporting aspects of predictive coding in the sensory cortex.

Indexed as

Auditory CortexEvoked Potentials, AuditoryAcoustic StimulationNeuronsCP: Neurosciencedecision makingmacaque monkeyoddball paradigmP300predictive coding theory

Identifiers

PMID38421870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.