Evidence map›Paper›PMID 38421393›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Acoustics and aerodynamic effects following glottal and infraglottal medialization in an excised larynx model.

Liran Oren, Alexandra Maddox, Charles Farbos de Luzan, Changchun Xie, Rebecca Howell, Gregory Dion, Ephraim Gutmark, Sid Khosla

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Infraglottal Medialization: Increasing Vocal Fold Stiffness Gradient for Improved Vocal Efficiency.Journal of voice : official journal of the Voice Foundation · 2024
    Article
  4. Characterization of the Vertical Stiffness Gradient in Cadaveric Human and Excised Canine Larynges.Journal of voice : official journal of the Voice Foundation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Liran OrenDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA. liran.oren@uc.edu.ORCID http://orcid.org/0000-0002-3232-6799
Alexandra MaddoxDepartment of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, OH, USA.
Charles Farbos de LuzanDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Changchun XieDepartment of Environmental and Public Health Sciences, University of Cincinnati, Cincinnati, OH, USA.
Rebecca HowellDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Gregory DionDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
Ephraim GutmarkDepartment of Aerospace Engineering and Engineering Mechanics, University of Cincinnati, Cincinnati, OH, USA.
Sid KhoslaDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, OH, USA.
University of Cincinnati · US

Funding

The Relationships Between Vortices, Acoustics, and Vibration in Vocal Fold AsymmetriesR01DC009435 · NIDCD · UNIVERSITY OF CINCINNATI · PI OREN, LIRAN · 2009 to 2025
$8.5M
NIDCD NIH HHS R01 DC009435NIDCD NIH HHS R01DC009435
6 · The paper itself

Abstract

objectiveThis study aimed to investigate the impact of the implant's vertical location during Type 1 Thyroplasty (T1T) on acoustics and glottal aerodynamics using excised canine larynx model, providing insights into the optimal technique for treating unilateral vocal fold paralysis (UVFP).

methodsMeasurements were conducted in six excised canine larynges using Silastic implants. Two implant locations, glottal and infraglottal, were tested for each larynx at low and high subglottal pressure levels. Acoustic and intraglottal flow velocity field measurements were taken to assess vocal efficiency (VE), cepstral peak prominence (CPP), and the development of intraglottal vortices.

resultsThe results indicated that the implant's vertical location significantly influenced vocal efficiency (p = 0.045), with the infraglottal implant generally yielding higher VE values. The effect on CPP was not statistically significant (p = 0.234). Intraglottal velocity field measurements demonstrated larger glottal divergence angles and stronger vortices with the infraglottal implant.

conclusionThe findings suggest that medializing the paralyzed fold at the infraglottal level rather than the glottal level can lead to improved vocal efficiency. The observed larger divergence angles and stronger intraglottal vortices with infraglottal medialization may enhance voice outcomes in UVFP patients. These findings have important implications for optimizing T1T procedures and improving voice quality in individuals with UVFP. Further research is warranted to validate these results in clinical settings.

Indexed as

LaryngoplastyLarynxVocal Cord ParalysisVoiceAcousticsAnimalsDogsGlottisHumansVocal CordsImplant locationIntraglottal flowMedialization laryngoplastyUnilateral vocal fold paralysisVocal efficiency

Identifiers

PMID38421393
PMCPMC11024032
OpenAlexW4392295598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.