Evidence map›Paper›PMID 38421193›Full record

ArticleMicrobiology spectrum2024

Epidrugs: alternative chemotherapy targeting

Sonam Kamble, Sakshi Singh, Akash Suresh, Siva Singothu, Debabrata Dandesena, Vasundhra Bhandari, Paresh Sharma

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sonam KambleNational Institute of Animal Biotechnology, Hyderabad, India.
Sakshi SinghNational Institute of Animal Biotechnology, Hyderabad, India.
Akash SureshNational Institute of Animal Biotechnology, Hyderabad, India.
Siva SingothuNational Institute of Pharmaceutical Education and Research, Hyderabad, India.
Debabrata DandesenaNational Institute of Animal Biotechnology, Hyderabad, India.
Vasundhra BhandariNational Institute of Animal Biotechnology, Hyderabad, India.
Paresh SharmaNational Institute of Animal Biotechnology, Hyderabad, India.ORCID 0000-0001-5340-2036
National Institute of Animal Biotechnology · INNational Institute of Pharmaceutical Education and Research (NIPER) - Ahmedabad · IN

Funding

SERB EMR/2017/001513
6 · The paper itself

Abstract

The growing emergence of resistance to current anti-theilerial agents necessitates the exploration of alternative approaches to drug discovery. This study evaluated the antiparasitic efficacy of 148 compounds derived from an epigenetic inhibitor library against the schizont stage of a

Indexed as

Cattle DiseasesHydroxamic AcidsNaphthalenesNaphthoquinonesParasitesTheileria annulataTheileriasisAnimalsCattleHumansMolecular Docking SimulationSchizontsHydroxamic AcidsmethylstatNaphthalenesNaphthoquinonesplumbagintrichostatin Aapicomplexanapoptosisdrug repurposingepigenetic inhibitorsTheileria

Identifiers

PMID38421193
PMCPMC10986487
OpenAlexW4392295799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.