ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024
Quantifying pH-induced changes in plasma strong ion difference during experimental acidosis: clinical implications for base excess interpretation.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Quantifying the effects of hemoglobin saturation on plasma strong ion difference during blood oxygenation and decarboxylation.Physiological reports · 2026Article
- A pragmatic approach to complex acid base disturbances of critical illness: the "Stewart light".Intensive care medicine · 2026Article
- Effective buffers in intravenous solutions: reconciling the acid-base effects of organic anions.Critical care (London, England) · 2026Article
- Fluid-induced acid-base variations in postoperative critically ill patients: physiological determinants and renal response.Frontiers in medicine · 2026Article
- Structural Instability of Human Serum Albumin during Microparticles Synthesis.ACS applied bio materials · 2025Article
- Stewart's theory and acid-base changes induced by crystalloid infusion in humans: a randomized physiological trial.Annals of intensive care · 2025Article
- Article
- On acid-base bilingualism.Intensive care medicine · 2025Article
- Understanding buffering of metabolic acidosis in critical illness.Intensive care medicine · 2024Article
Corrections and comments
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Authors and funding
14 authors at 9 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is commonly assumed that changes in plasma strong ion difference (SID) result in equal changes in whole blood base excess (BE). However, at varying pH, albumin ionic-binding and transerythrocyte shifts alter the SID of plasma without affecting that of whole blood (SID
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.