Evidence map›Paper›PMID 38420618›Full record

ArticleOne earth (Cambridge, Mass.)2024

Ozone-related acute excess mortality projected to increase in the absence of climate and air quality controls consistent with the Paris Agreement.

Nina G G Domingo, Arlene M Fiore, Jean-Francois Lamarque, Patrick L Kinney, Leiwen Jiang, Antonio Gasparrini, Susanne Breitner, Eric Lavigne, Joana Madureira, Pierre Masselot and 36 more

Abstract read
In one paragraph

Article in One earth (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Parenchymal and inflammatory responses to ozone exposure in the aging healthy and surfactant protein C mutant lung.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors.

Nina G G DomingoDepartment of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06510, USA.
Arlene M FioreDepartment of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Jean-Francois LamarqueClimate and Global Dynamics Laboratory, National Center for Atmospheric Research, Boulder, CO, USA.
Patrick L KinneyDepartment of Environmental Health, School of Public Health, Boston University, Boston, MA 02118, USA.
Leiwen JiangAsian Demographic Research Institute, Shanghai University, Shanghai 200444, China.
Antonio GasparriniEnvironment & Health Modelling (EHM) Lab, Department of Public Health Environments and Society, London School of Hygiene & Tropical Medicine, London, UK.
Susanne BreitnerIBE-Chair of Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany.
Eric LavigneSchool of Epidemiology & Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Joana MadureiraEnvironmental Health Department of the National Health Institute of Health Dr. Ricardo Jorge, Porto, Portugal.
Pierre MasselotDepartment of Public Health Environments and Society, London School of Hygiene & Tropical Medicine, London, UK.
Susana das Neves Pereira da SilvaEnvironmental Health Department of the National Health Institute of Health Dr. Ricardo Jorge, Porto, Portugal.
Chris Fook Sheng NgDepartment of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Jan KyselýInstitute of Atmospheric Physics, Czech Academy of Sciences, Prague, Czech Republic.
Yuming GuoDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, NSW, Australia.
Shilu TongSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD, Australia.
Haidong KanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
Aleš UrbanInstitute of Atmospheric Physics, Czech Academy of Sciences, Prague, Czech Republic.
Hans OrruDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Marek MaasikmetsEstonian Environmental Research Centre, Tallinn, Estonia.
Mathilde PascalSanté Publique France, Department of Environmental Health, French National Public Health Agency, Saint Maurice, France.
Klea KatsouyanniDepartment of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Athens, Greece.
Evangelia SamoliDepartment of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Athens, Greece.
Matteo ScortichiniDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Massimo StafoggiaDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Masahiro HashizumeDepartment of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Barrak AlahmadDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Magali Hurtado DiazDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
César De la Cruz ValenciaDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Noah ScovronickDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Rebecca M GarlandDepartment of Geography, Geoinformatics and Meteorology, University of Pretoria, Pretoria, South Africa.
Ho KimGraduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Whanhee LeeDepartment of Occupational and Environmental Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.
Aurelio TobiasSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Carmen ÍñiguezDepartment of Statistics and Computational Research, Universitat de València, València, Spain.
Bertil ForsbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Christofer ÅströmDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Martina S RagettliSwiss Tropical and Public Health Institute, Basel, Switzerland.
Yue Leon GuoEnvironmental and Occupational Medicine, National Taiwan University (NTU) College of Medicine and NTU Hospital, Taipei, Taiwan.
Shih-Chun PanNational Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.
Valentina ColistroThe Centre on Climate Change and Planetary Health, London School of Hygiene & Tropical Medicine, London, UK.
Michelle BellSchool of the Environment, Yale University, New Haven, CT, USA.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Alexandra Schneider *Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Ana M Vicedo-Cabrera *Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Kai Chen *Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06510, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Extreme Heat and Acute Myocardial Infarction: Effect Modifications by Sex, Medical History, and Air PollutionR01HL169171 · NHLBI · YALE UNIVERSITY · PI Kai Chen · 2023 to 2026
$2.9M
Medical Research Council MR/V034162/1NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL169171
6 · The paper itself

Abstract

Short-term exposure to ground-level ozone in cities is associated with increased mortality and is expected to worsen with climate and emission changes. However, no study has yet comprehensively assessed future ozone-related acute mortality across diverse geographic areas, various climate scenarios, and using CMIP6 multi-model ensembles, limiting our knowledge on future changes in global ozone-related acute mortality and our ability to design targeted health policies. Here, we combine CMIP6 simulations and epidemiological data from 406 cities in 20 countries or regions. We find that ozone-related deaths in 406 cities will increase by 45 to 6,200 deaths/year between 2010 and 2014 and between 2050 and 2054, with attributable fractions increasing in all climate scenarios (from 0.17% to 0.22% total deaths), except the single scenario consistent with the Paris Climate Agreement (declines from 0.17% to 0.15% total deaths). These findings stress the need for more stringent air quality regulations, as current standards in many countries are inadequate.

Identifiers

PMID38420618
PMCPMC7615682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.