Evidence map›Paper›PMID 38420498›Full record

ArticleJournal of biomedical optics2024

Photoacoustic/ultrasound dual-modality imaging for marker clip localization in neoadjuvant chemotherapy of breast cancer.

Handi Deng, Yizhou Bai, Jiaxuan Xiang, Zhaoyue Li, Peiliang Zhao, Yawen Shi, Wubing Fu, Yuwen Chen, Minggang Fu, Cheng Ma and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Handi DengTsinghua University, Beijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Beijing, China.
Yizhou BaiTsinghua University, Institute for Precision Healthcare, Beijing, China.
Jiaxuan XiangTsingPAI Technology Co., Ltd., Beijing, China.
Zhaoyue LiBeijing Tsinghua Changgung Hospital, Tsinghua University, School of Clinical Medicine, Beijing, China.ORCID 0000-0002-8485-1843
Peiliang ZhaoBeijing Tsinghua Changgung Hospital, Tsinghua University, School of Clinical Medicine, Beijing, China.
Yawen ShiTsinghua University, Beijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Beijing, China.
Wubing FuTsingPAI Technology Co., Ltd., Beijing, China.
Yuwen ChenTsinghua University, Beijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Beijing, China.
Minggang FuZhuhai Hospital Affiliated with Jinan University, Jinan University, Department of Thyroid and Galactophore Surgery, Zhuhai, China.
Cheng MaTsinghua University, Beijing National Research Center for Information Science and Technology, Department of Electronic Engineering, Beijing, China.
Bin LuoTsinghua University, Institute for Precision Healthcare, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: To ensure precise tumor localization and subsequent pathological examination, a metal marker clip (MC) is placed within the tumor or lymph node prior to neoadjuvant chemotherapy for breast cancer. However, as tumors decrease in size following treatment, detecting the MC using ultrasound imaging becomes challenging in some patients. Consequently, a mammogram is often required to pinpoint the MC, resulting in additional radiation exposure, time expenditure, and increased costs. Dual-modality imaging, combining photoacoustic (PA) and ultrasound (US), offers a promising solution to this issue. Aim: Our objective is to localize the MC without radiation exposure using PA/US dual-modality imaging. Approach: A PA/US dual-modality imaging system was developed. Utilizing this system, both phantom and clinical experiments were conducted to demonstrate that PA/US dual-modality imaging can effectively localize the MC. Results: The PA/US dual-modality imaging can identify and localize the MC. In clinical trials encompassing four patients and five MCs, the recognition rate was Conclusions: We effectively localized the MC in real time using PA/US dual-modality imaging. Unlike other techniques, the new method enables surgeons to pinpoint nodules both preoperatively and intraoperatively. In addition, it boasts non-radioactivity and is comparatively cost-effective.

Indexed as

Breast NeoplasmsFemaleHumansLymph NodesNeoadjuvant TherapySurgical InstrumentsUltrasonographymarker clipneoadjuvant chemotherapyPA/US dual-modality imagingtumor localization

Identifiers

PMID38420498
PMCPMC10901241

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.