Evidence map›Paper›PMID 38420381›Full record

ArticleHeliyon2024

Does PaCO

Audrey Thomas, Sandrine Jaffré, Vianney Guardiolle, Tanguy Perennec, Frédéric Gagnadoux, François Goupil, Cédric Bretonnière, Vivien Danielo, Jean Morin, François-Xavier Blanc

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Enhancing respiratory function in neuromuscular disease: the role of non-invasive ventilation. A narrative review.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Audrey ThomasNantes Université, CHU Nantes, Department of Respiratory Medicine, l'institut du thorax, Nantes, France.
Sandrine JaffréNantes Université, CHU Nantes, Department of Respiratory Medicine, l'institut du thorax, Nantes, France.
Vianney GuardiolleNantes Université, CHU Nantes, Data Clinic, INSERM CIC 1413, Nantes, France.
Tanguy PerennecRadiotherapy Department, West Cancer Institute, Saint Herblain, France.
Frédéric GagnadouxDepartment of Respiratory and Sleep Medicine, Angers University Hospital, Angers, France.
François GoupilDepartment of Respiratory Diseases, Le Mans General Hospital, Le Mans, France.
Cédric BretonnièreNantes Université, CHU Nantes, Department of Respiratory Medicine, l'institut du thorax, Nantes, France.
Vivien DanieloNantes Université, CHU Nantes, Department of Respiratory Medicine, l'institut du thorax, Nantes, France.
Jean MorinNantes Université, CHU Nantes, Department of Respiratory Medicine, l'institut du thorax, Nantes, France.
François-Xavier BlancNantes Université, CHU Nantes, Department of Respiratory Medicine, l'institut du thorax, Nantes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Non-invasive ventilation (NIV) improves survival of patients with chronic respiratory failure (CRF). Most often, pressure settings are made to normalize arterial blood gases. However, this objective is not always achieved due to intolerance to increased pressure or poor compliance. Few studies have assessed the effect of persistent hypercapnia on ventilated patients' survival. Data from the Pays de la Loire Respiratory Health Research Institute cohort were analyzed to answer this question. Study design and methods: NIV-treated adults enrolled between 2009 and 2019 were divided into 5 subgroups: obesity-hypoventilation syndrome (OHS), COPD, obese COPD, neuromuscular disease (NMD) and chest wall disease (CWD). PaCO Results: Data from 431 patients were analyzed. Median survival was 103 months and 148 patients died. Overall, PaCO Conclusion: Moderate residual hypercapnia under NIV does not negatively impact survival in CRF patients. In individuals with poor tolerance of pressure increases, residual hypercapnia can therefore be tolerated under long-term NIV. Larger studies, especially with a higher number of patients with residual PaCO

Indexed as

Chronic obstructive pulmonary diseaseChronic respiratory failureHypercapniaNon-invasive ventilationObesity-hypoventilation syndromeSurvival

Identifiers

PMID38420381
PMCPMC10901024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.