Evidence map›Paper›PMID 38420313›Full record

ArticleBiomedical optics express2023

Potential vision tester using adaptive optics, Maxwellian view, and small pupil.

Ann E Elsner, Joel A Papay, Vamsi Parimi, Hae Won Jung, Christopher A Clark, Stephen A Burns, Thomas J Gast

Abstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Photoreceptor layer elevation due to subretinal fluid: Impact on visual acuity measurements and simulation from biometrics.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  5. Wavefront aberrations in aging measured with Hartmann-Shack at 3- and 5-mm pupil sizes.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ann E ElsnerSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.ORCID https://orcid.org/0000-0002-9040-9672
Joel A PapayAeon Imaging, LLC, Bloomington, IN 47403, USA.ORCID https://orcid.org/0000-0002-9930-4754
Vamsi ParimiSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.ORCID https://orcid.org/0000-0003-3959-7206
Hae Won JungAeon Imaging, LLC, Bloomington, IN 47403, USA.ORCID https://orcid.org/0000-0002-4621-427X
Christopher A ClarkSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.
Stephen A BurnsSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.ORCID https://orcid.org/0000-0001-5348-035X
Thomas J GastSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.

Funding

Visual acuity and functional measurements in the aging eyeR44EY030829 · NEI · AEON IMAGING, LLC · PI ELSNER, ANN E, GAST, THOMAS J. · 2022 to 2023
$1.4M
Visual acuity and functional measurements in the aging eyeR41EY030829 · NEI · AEON IMAGING, LLC · PI ELSNER, ANN E · 2019 to 2019
$226k
NEI NIH HHS R41 EY030829NEI NIH HHS R44 EY030829
6 · The paper itself

Abstract

We demonstrate a free-space, trolley-mounted potential vision tester (PVT), designed to study and improve the accuracy of visual acuity (VA) measurements in the aging eye. Key features include a high-resolution visual display presented in Maxwellian view, a 3 mm pupil to limit wavefront (WF) aberrations, and a moderate cost deformable mirror to induce or correct higher order optical aberrations. The visual display supported accurate measurement of visual acuities down to 20/5. The moderate cost, piezo deformable mirror induced seven nominal aberrations, calibrated as 0, -0.32, -0.23, + 0.27, and +0.39 microns spherical aberration; + 0.49 microns Y coma; and -0.51 microns X coma. A custom Hartmann Shack (HS) calibration (HSc) system demonstrated that induced aberrations were repeatable and stable. A Badal optometer provided the coarse focus. WF aberrations were measured for five normal subjects with a commercially available HS device (HSP) (OCULUS Pentacam AXL Wave), providing estimates of WF errors for 3 mm and other pupil sizes. VA was measured using four alternative forced-choice for a single black on white E stimulus in each trial. Using the method of constant stimuli yielded robust standard deviation measurements. The 50% fit for VA plotted against induced aberration resulted in linear functions for each subject for the range of our positive and negative spherical aberration data. Subjects differed, but higher order terms were unnecessary to describe data across spherical aberrations.

Identifiers

PMID38420313
PMCPMC10898563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.