Evidence map›Paper›PMID 38420219›Full record

ReviewEClinicalMedicine2024

Recommendations for surveillance of pulmonary dysfunction among childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Maria Otth, Rahel Kasteler, Renée L Mulder, Jennifer Agrusa, Saro H Armenian, Dana Barnea, Anne Bergeron, Neel S Bhatt, Stephen J Bourke, Louis S Constine and 19 more

Open access · goldAbstract readReview
In one paragraph

Review in EClinicalMedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Cohort Profile Update: The Swiss Childhood Cancer Survivor Cohort.International journal of epidemiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Exercise-induced symptoms in young childhood cancer survivors.Journal of cancer survivorship : research and practice · 2025
    Article
  12. Observational
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 19 institutions in 7 countries.

Maria OtthDepartment of Oncology, Haematology, Immunology, Stem Cell Transplantation and Somatic Gene Therapy, University Children's Hospital Zurich, Zurich, Switzerland.
Rahel KastelerDepartment of Oncology, Haematology, Immunology, Stem Cell Transplantation and Somatic Gene Therapy, University Children's Hospital Zurich, Zurich, Switzerland.
Renée L MulderPrincess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Jennifer AgrusaDepartment of Pediatric Hematology Oncology, C.S. Mott Children's Hospital, University of Michigan, Michigan, USA.
Saro H ArmenianDepartment of Pediatrics, City of Hope, Duarte, CA, USA.
Dana BarneaDepartment of Hematology and Department of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Anne BergeronHôpitaux Universitaires de Genève, Université de Genève, Genève, Switzerland.
Neel S BhattClinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Stephen J BourkeDepartment of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom.
Louis S ConstineDepartments of Radiation Oncology and Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Myrofora GoutakiInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Daniel M GreenDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
Ulrike HennewigUniversity Hospital of Giessen and Marburg, Pediatric Hematology and Oncology, Giessen, Germany.
Veronique HoudouinAP-HP, Hôpital Robert Debré, Service de Pneumopédiatrie, Paris, France.
Melissa M HudsonDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
Leontien KremerPrincess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Philipp LatzinDivision of Paediatric Respiratory Medicine and Allergology, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Antony NgDepartment of Paediatric Oncology, Royal Hospital for Children, Bristol, UK.
Kevin C OeffingerDepartment of Community and Family Medicine, Duke University School of Medicine, Durham, NC, USA.
Christina SchinderaInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Roderick SkinnerDepartment of Paediatric and Adolescent Haematology/Oncology, Great North Children's Hospital and Newcastle University Centre for Cancer, Newcastle upon Tyne, UK.
Grit SommerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Saumini SrinivasanDivision of Pulmonology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.
Dennis C StokesDivision of Pulmonology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.
Birgitta VersluysPrincess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Nicolas WaespeInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Daniel J WeinerDivision of Pediatric Pulmonology, University of Pittsburgh, Pittsburgh, PA, USA.
Andrew C DietzShape Therapeutics, Inc., Seattle, WA, USA.
Claudia E KuehniInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
University of Bern · CHPrincess Máxima Center · NLSt. Jude Children's Research Hospital · USUniversity of Geneva · CHUniversity of Tennessee Health Science Center · USAssistance Publique – Hôpitaux de Paris · FRBristol Royal Hospital for Children · GBCity of Hope · USDuke University · USFred Hutch Cancer Center · USGreat North Children's Hospital · GBRoyal Victoria Infirmary · GBTel Aviv Sourasky Medical Center · ILUniversitätsklinikum Gießen und Marburg · DEUniversity Children's Hospital Zurich · CHUniversity of Lucerne · CHUniversity of Michigan · USUniversity of Pittsburgh · USUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood, adolescent, and young adult (CAYA) cancer survivors are at risk of pulmonary dysfunction. Current follow-up care guidelines are discordant. Therefore, the International Late Effects of Childhood Cancer Guideline Harmonization Group established and convened a panel of 33 experts to develop evidence-based surveillance guidelines. We critically reviewed available evidence regarding risk factors for pulmonary dysfunction, types of pulmonary function testing, and timings of surveillance, then we formulated our recommendations. We recommend that CAYA cancer survivors and healthcare providers are aware of reduced pulmonary function risks and pay vigilant attention to potential symptoms of pulmonary dysfunction, especially among survivors treated with allogeneic haematopoietic stem cell transplantation, thoracic radiotherapy, and thoracic surgery. Based on existing limited evidence and current lack of interventions, our panel recommends pulmonary function testing only for symptomatic survivors. Since scarce existing evidence informs our recommendation, we highlight the need for prospective collaborative studies to address pulmonary function knowledge gaps among CAYA cancer survivors.

Indexed as

Childhood cancer/malignancyLate effectsLung functionRespiratorySurvivors

Identifiers

PMID38420219
PMCPMC10900250
OpenAlexW4391951089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.