ArticleCurrent research in toxicology2024
Thallium - poisoner's poison: An overview and review of current knowledge on the toxicological effects and mechanisms.
Article in Current research in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 48 citations in OpenAlex.
- Metal and metal mixture biomarkers across three U.S. cohorts: MASALA, MESA-LA, and Strong Heart Family Study.Journal of exposure science & environmental epidemiology · 2026Article
- T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review).Oncology reports · 2026Review
- Traces of Elements in the Electrochemical Reductive Amination of Acetone: Uncovering Bi as Substitute for Pb.Angewandte Chemie (International ed. in English) · 2026Article
- Effect of Exogenous Addition of Microplastics on the Ability of Plants and Soil to Accumulate Thallium.Toxics · 2026Article
- Movement disorders associated with diarrhoea.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Association of metal and metalloid exposure with cardiovascular-kidney-metabolic syndrome: mediation by inflammation, oxidative stress, and aging.BMC public health · 2025Article
- Serum heavy metal levels from tobacco smoke and Buerger's disease.Scientific reports · 2025Article
- The Impact of Arsenic, Cadmium, Lead, Mercury, and Thallium Exposure on the Cardiovascular System and Oxidative Mechanisms in Children.Current issues in molecular biology · 2025Review
- Transplacental and genotoxicity effects of thallium(I) during organogenesis in mice.Toxicology reports · 2025Article
- Machine learning prediction model with shap interpretation for chronic bronchitis risk assessment based on heavy metal exposure: a nationally representative study.BMC pulmonary medicine · 2025Article
- Rapid Determination of Toxic Trace Metals As, Hg, Tl, and Pb in Hair by Monochromatic Excitation X-ray Fluorescence Spectrometry.Biological trace element research · 2025Article
- Case report: Successful treatment of a thallium sulfate intoxication in a dog with use of Prussian blue.Frontiers in veterinary science · 2025Article
- Thallium (III) disrupts the cell cycle and induces oxidative DNA damage in human lymphocytesCurrent research in toxicology · 2025Article
- Article
- The Impact of Thallium Exposure in Public Health and Molecular Toxicology: A Comprehensive Review.International journal of molecular sciences · 2024Review
- Dissociation of mitochondrial and ribosomal biogenesis during thallium administration in rat kidney.PloS one · 2024Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thallium (Tl) is one of the most toxic metals and its historic use in homicides has led it to be known as "the poisoner's poison." This review summarizes the methods for identifying Tl and determining its concentrations in biological samples in recently reported poisoning cases, as well as the toxicokinetics, toxicological effects, toxicity mechanisms, and detoxication methods of Tl. Recent findings regarding Tl neurotoxicological pathways and toxicological effects of Tl during pregnancy are also presented. Confirmation of elevated Tl concentrations in blood, urine, or hair is indispensable for diagnosing Tl poisoning. The kidneys show the highest Tl concentration within 24 h after ingestion, while the brain shows the highest concentration thereafter. Tl has a very slow excretion rate due to its large distribution volume. Following acute exposure, gastrointestinal symptoms are observed at an early stage, and neurological dysfunction is observed later: Tl causes the most severe damage in the central nervous system. Alopecia and Mees' lines in the nails are observed within 1 month after Tl poisoning. The toxicological mechanism of Tl is considered to be interference of vital potassium-dependent processes with Tl
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