Evidence map›Paper›PMID 38420049›Full record

ArticleCureus2024

Bullous Pemphigoid Associated With the Use of Sacubitril/Valsartan: A Case Report and Literature Review.

Daniel A Martin Arsanios, Lina M Gómez-Álvarez, Natalia Muñoz-Angulo, Claudia Montealegre, Elias Quintero Muñoz, Carlos Calderón-Vargas

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Daniel A Martin ArsaniosInternal Medicine, Hospital Universitario de La Samaritana, Bogotá, COL.
Lina M Gómez-ÁlvarezInternal Medicine, Universidad de La Sabana, Bogotá, COL.
Natalia Muñoz-AnguloInternal Medicine, Universidad El Bosque, Bogotá, COL.
Claudia MontealegreInternal Medicine, Fundación Universitaria Juan N. Corpas, Bogotá, COL.
Elias Quintero MuñozInternal Medicine, Universidad de La Sabana, Bogotá, COL.
Carlos Calderón-VargasInternal Medicine, Hospital Universitario de La Samaritana, Bogotá, COL.
Universidad de La Sabana · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bullous pemphigoid (BP) is a complex autoimmune blistering disease with an increased incidence in the comorbid population, particularly among older adults. The occurrence of drug-induced BP is associated with an underlying genetic predisposition, triggering an enhanced immune response, the formation of autoantibodies, and alterations in antigenic properties within the basement membrane zone. With over 90 identified drugs capable of precipitating BP, we present the case of an 87-year-old woman with comorbidities who experienced a medication change from losartan to sacubitril/valsartan. Three months later, erythematous lesions appeared on her lower limbs, progressing to a generalized rash accompanied by itching. Over the following month, these lesions evolved into tense blisters with serous content and intense pain. Suspecting the medication switch to sacubitril/valsartan as the cause, the drug was discontinued, and immunomodulatory treatment was initiated, resulting in a notable improvement in the lesions.

Indexed as

adverse reactionsblistersbullous pemphigoidsacubitril/valsartanskin lesions

Identifiers

PMID38420049
PMCPMC10900178
OpenAlexW4391311148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.