Evidence map›Paper›PMID 38419975›Full record

ArticleCrystEngComm2024

An unusual ionic cocrystal of ponatinib hydrochloride: characterization by single-crystal X-ray diffraction and ultra-high field NMR spectroscopy.

Alexander J Stirk, Sean T Holmes, Fabio E S Souza, Ivan Hung, Zhehong Gan, James F Britten, Allan W Rey, Robert W Schurko

Abstract read
In one paragraph

Article in CrystEngComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. A focus on applyingChemical science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander J StirkApotex Pharmachem Inc. Brantford ON N3T 6B8 Canada.ORCID https://orcid.org/0000-0002-4973-0747
Sean T HolmesDepartment of Chemistry & Biochemistry, Florida State University Tallahassee FL 32306 USA rschurko@fsu.edu.ORCID https://orcid.org/0000-0002-5821-9641
Fabio E S SouzaApotex Pharmachem Inc. Brantford ON N3T 6B8 Canada.
Ivan HungNational High Magnetic Field Laboratory Tallahassee FL 32310 USA.ORCID https://orcid.org/0000-0001-8916-739X
Zhehong GanNational High Magnetic Field Laboratory Tallahassee FL 32310 USA.ORCID https://orcid.org/0000-0002-9855-5113
James F BrittenMAX Diffraction Facility, McMaster University Hamilton ON L8S 4M1 Canada.
Allan W ReyApotex Pharmachem Inc. Brantford ON N3T 6B8 Canada.
Robert W SchurkoDepartment of Chemistry & Biochemistry, Florida State University Tallahassee FL 32306 USA rschurko@fsu.edu.ORCID https://orcid.org/0000-0002-5093-400X

Funding

TR&D3-SCHP41GM122698 · NIGMS · FLORIDA STATE UNIVERSITY · PI BREY, WILLIAM W, CROSS, TIMOTHY A · 2017 to 2021
$6.7M
National Resource for Advanced NMR TechnologyRM1GM148766 · NIGMS · FLORIDA STATE UNIVERSITY · PI William W Brey, Joanna R Long · 2023 to 2026
$4.9M
NIGMS NIH HHS P41 GM122698NIGMS NIH HHS RM1 GM148766
6 · The paper itself

Abstract

This study describes the discovery of a unique ionic cocrystal of the active pharmaceutical ingredient (API) ponatinib hydrochloride (

Identifiers

PMID38419975
PMCPMC10897533

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.