Evidence map›Paper›PMID 38419710›Full record

ArticleFrontiers in neurology2024

Post-COVID central hypersomnia, a treatable trait in long COVID: 4 case reports.

Clémence Morelli-Zaher, Andrea Vremaroiu-Coman, Nicolas Coquoz, Léon Genecand, Marco Altarelli, Alzbeta Binkova, Isabelle Frésard, Pierre-Olivier Bridevaux, Grégoire Gex

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Clémence Morelli-ZaherDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Andrea Vremaroiu-ComanDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Nicolas CoquozDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Léon GenecandDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Marco AltarelliDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Alzbeta BinkovaDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Isabelle FrésardDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Pierre-Olivier BridevauxDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Grégoire GexDivision of Pulmonology, Centre Hospitalier du Valais Romand, Hôpital du Valais, Sion, Switzerland.
Hôpital du Valais · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Fatigue is the most commonly reported post-COVID symptom. A minority of patients also report excessive daytime sleepiness, which could be a target for treatment. Methods: Among 530 patients with a post-COVID condition, those with excessive daytime sleepiness were systematically assessed for objective central hypersomnia, with exclusion of all cases not clearly attributable to SARS-CoV-2 infection. Results: Four cases of post-COVID central hypersomnia were identified, three fulfilling the criteria of the 3rd International Classification of Sleep Disorders for idiopathic hypersomnia, and one for type II narcolepsy. We report here their clinical history, sleep examination data and treatment, with a favorable response to methylphenidate in three cases and spontaneous resolution in one case. Conclusion: We highlight the importance of identifying cases of post-COVID central hypersomnia, as it may be a treatable trait of a post-COVID condition.

Indexed as

central hypersomniaidiopathic hypersomnialong COVIDmethylphenidatenarcolepsypost-COVID conditionSARS-CoV-2treatment

Identifiers

PMID38419710
PMCPMC10899667
OpenAlexW4391818517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.