Evidence map›Paper›PMID 38419663›Full record

ArticleFrontiers in neuroscience2024

Associations between gut microbiota and adverse neurodevelopmental outcomes in preterm infants: a two-sample Mendelian randomization study.

Yuqian Wang, Tongfei Cheng, Yifan Cui, Danyang Qu, Xin Peng, Liu Yang, Xuwu Xiao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yuqian WangDepartment of Graduate, Dalian Medical University, Dalian, Liaoning, China.
Tongfei ChengDepartment of Pediatrics, The Affiliated Women's and Children's Hospital of Qingdao University, Qingdao, Shandong, China.
Yifan CuiDepartment of Pediatrics, Dalian Women and Children's Medical Group, Dalian, Liaoning, China.
Danyang QuDepartment of Pediatrics, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
Xin PengDepartment of Pediatrics, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
Liu YangDepartment of Pediatrics, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
Xuwu XiaoDepartment of Graduate, Dalian Medical University, Dalian, Liaoning, China.
Dalian Maternal and Child Health Hospital · CNDalian Medical University · CNSecond Affiliated Hospital of Dalian Medical University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota are associated with adverse neurodevelopmental outcomes in preterm infants; however, the precise causal relationship remains unclear. In this study, we conducted a two-sample Mendelian randomization (MR) analysis to comprehensively study the relationship between gut microbiota and adverse neurodevelopmental outcomes in preterm infants and identify specific causal bacteria that may be associated with the occurrence and development of adverse neurodevelopmental outcomes in preterm infants. The genome-wide association analysis (GWAS) of the MiBioGen biogroup was used as the exposure data. The GWAS of six common adverse neurodevelopmental outcomes in premature infants from the FinnGen consortium R9 was used as the outcome data. Genetic variations, namely, single nucleotide polymorphisms (SNPs) below the locus-wide significance level (1 × 10

Indexed as

causal relationshipgenome-wide association study polymorphismgut microbiotainstrumental variableMendelian randomizationneurodevelopmental outcomepreterm infantsingle nucleotide gastrointestinal microbiome

Identifiers

PMID38419663
PMCPMC10899413
OpenAlexW4391818813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.