Evidence map›Paper›PMID 38419540›Full record

ArticleAnimal bioscience2024

Identification of new major histocompatibility complex-B Haplotypes in Bangladesh native chickens.

Thisarani Kalhari Ediriweera, Prabuddha Manjula, Jaewon Kim, Jin Hyung Kim, Seonju Nam, Minjun Kim, Eunjin Cho, Mohammad Shamsul Alam Bhuiyan, Md Abdur Rashid, Jun Heon Lee

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Article in Animal bioscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Diversity of MHC-B SNP haplotypes in the Vietnamese Ri chicken.Journal of animal science and technology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thisarani Kalhari EdiriweeraDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Korea.
Prabuddha ManjulaDepartment of Animal Science, Uva Wellassa University, Badulla 90000, Sri Lanka.
Jaewon KimDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Jin Hyung KimDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Seonju NamDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Minjun KimDivision of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
Eunjin ChoDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Korea.
Mohammad Shamsul Alam BhuiyanDepartment of Animal Breeding and Genetics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Md Abdur RashidPoultry Production Research Division, Bangladesh Livestock Research Institute, Dhaka-1341, Bangladesh.
Jun Heon LeeDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Korea.

Funding

National Research Foundation of Korea 2022R1F1A1064025
6 · The paper itself

Abstract

objectiveThe major histocompatibility complex in chicken demonstrates a great range of variations within varities, breeds, populations and that can eventually influence their immuneresponses. The preset study was conducted to understand the major histocompatibility complex-B (MHC-B) variability in five major populations of Bangladesh native chicken: Aseel, Hilly, Junglefowl, Non-descript Deshi, and Naked Neck.

methodsThese five major populations of Bangladesh native chicken were analyzed with a subset of 89 single nucleotide polymorphisms (SNPs) in the high-density MHC-B SNP panel and Kompetitive Allele-Specific polymerase chain reaction genotyping was applied. To explore haplotype diversity within these populations, the results were analyzed both manually and computationally using PHASE 2.1 program. The phylogenetic investigations were also performed using MrBayes program.

resultsA total of 136 unique haplotypes were identified within these five Bangladesh chicken populations, and only one was shared (between Hilly and Naked Neck). Phylogenetic analysis showed no distinct haplotype clustering among the five populations, although they were shared in distinct clades; notably, the first clade lacked Naked Neck haplotypes.

conclusionThe present study discovered a set of unique MHC-B haplotypes in Bangladesh chickens that could possibly cause varied immune reponses. However, further investigations are required to evaluate their relationships with global chicken populations.

Indexed as

Bangladesh Native ChickenHaplotypesKompetitive Allele Specific Polymerase Chain Reaction (PCR)Major Histocompatibility Complex-BPhylogeny

Identifiers

PMID38419540
PMCPMC11065705

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