Evidence map›Paper›PMID 38419283›Full record

ArticleCancer reports (Hoboken, N.J.)2024

Case series: Stenotrophomonas maltophilia in pediatric oncology patients.

Sanila Sarkar, Lea M Stitzlein, Emily Rav, Miriam B Garcia, Shehla Razvi, Michael Chang, Ramia Zakhour

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Hemorrhagic Pneumonia Caused byMedicina (Kaunas, Lithuania) · 2024
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sanila SarkarDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0009-0007-4421-4915
Lea M StitzleinDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Emily RavDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Miriam B GarciaDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Shehla RazviDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michael ChangDivision of Infectious Diseases, McGovern Medical School at UT Health Houston, and Children's Memorial Hermann Hospital, Houston, Texas, USA.
Ramia ZakhourDivision of Infectious Diseases, McGovern Medical School at UT Health Houston, and Children's Memorial Hermann Hospital, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · USMemorial Hermann · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStenotrophomonas maltophilia is a bacterial pathogen that can be fatal in hospitalized and immunocompromised patients with mortality as high as 69%. Pediatric cancer patients often have risk factors that are common for this infection, making them particularly susceptible. Managing S. maltophilia is especially challenging as it has inherent resistance to several antibiotics. Furthermore, soft tissue infections in neutropenic patients may deviate from the typical clinical presentation of S. maltophilia. CASE DETAILS: This case series describes an in-depth examination of three cases involving immunocompromised pediatric patients with S. maltophilia infections. Each case exhibited a distinct clinical presentation, encompassing infection of the blood, lung, and skin, which highlights the variability in which S. maltophilia manifests in immunocompromised pediatric patients. These patients were treated at MD Anderson Cancer Center (MDACC) from 2020 to 2023, unfortunately resulting in fatality.

conclusionsThe study aims to provide valuable insights and guidance for the management of patients with S. maltophilia infections. Emphasizing a heightened clinical suspicion will potentially lead to early initiation of directed therapy against S. maltophilia. Timely intervention may play a pivotal role in improving patient outcomes and reduce further burden to the healthcare system.

Indexed as

NeoplasmsStenotrophomonas maltophiliaAnti-Bacterial AgentsChildHumansRisk FactorsAnti-Bacterial AgentsimmunocompromisedmalignancypediatricStenotrophomonas maltophilia

Identifiers

PMID38419283
PMCPMC10913069
OpenAlexW4392289417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.