Evidence map›Paper›PMID 38419107›Full record

ArticleWorld journal of surgical oncology2024

Mammographically detected breast clustered microcalcifications localized by chest thin-section computed tomography.

Xinjie Liu, Yuhan Bao, Laijian Sui, Jianqiao Cao, Yidan Wang, Chao Yu, Guangdong Qiao, Yizi Cong

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xinjie Liu *Surgery Department of West Area, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China.
Yuhan Bao *Department of Breast Surgery, The Second Hospital of Shandong University, 247 Beiyuan Street, Jinan, Shandong, 250031, P.R. China.
Laijian Sui *Department of Orthopedics and Arthrology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China.
Jianqiao CaoDepartment of Breast Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China.
Yidan WangDepartment of Breast Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China.
Chao YuDepartment of Breast Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China.
Guangdong QiaoDepartment of Breast Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China.
Yizi CongDepartment of Breast Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 20 Yuhuangding East Road, Yantai, Shandong, 264001, P.R. China. congyizi@163.com.
Qingdao University · CNYuhuangding Hospital · CNSecond Hospital of Shandong University · CN

Funding

Natural Science Foundation of Shandong Province ZR2021MH340Science and Technology Development Plan of Yantai City 2022YD028special funds for scientific research on breast diseases of Shandong Medical Association YXH2021ZX053Wu Jieping Medical Foundation Clinical Research Special Fund 320.6750.2020-20-4
6 · The paper itself

Abstract

backgroundTo explore the capability and clinical significance of chest thin-section computed tomography (CT) for localization of mammographically detected clustered microcalcifications.

methodsA total of 69 patients with 71 mammographically detected clustered microcalcifications received surgical biopsy under the guidance of mammography (MG), CT was used to localize calcifications combined with MG if calcifications can be seen on CT. Intraoperative mammography of the specimens were performed in all cases for identification of the resected microcalcifications. The clinical, imaging and pathological information of these patients were analyzed.

resultsA total of 42 (59.15%) cases of calcifications were localized by CT + MG, 29 (40.85%) cases were guided only by the mammography. All suspicious calcifications on the mammography were successfully removed. Pathological results showed 42 cases were cancer, 23 cases were benign, and 6 cases were atypical hyperplasia. The mean age in the CT + MG group was older than that of the MG group (54.12 vs. 49.27 years; P = 0.014). The maximum diameter of clusters of microcalcifications on mammography in the CT + MG group was larger than that of the MG group [(cranio-caudal view, 1.52 vs. 0.61 mm, P = 0.000; mediolateral oblique (MLO) view, 1.53 vs. 0.62 mm, P = 0.000)]. The gray value ratio (calcified area / paraglandular; MLO, P = 0.004) and the gray value difference (calcified area - paraglandular; MLO, P = 0.005) in the CT + MG group was higher than that of the MG group. Multivariate analysis showed that the max diameter of clusters of microcalcifications (MLO view) was a significant predictive factor of localization by CT in total patients (P = 0.001).

conclusionsAbout half of the mammographically detected clustered microcalcifications could be localized by thin-section CT. Maximum diameter of clusters of microcalcifications (MLO view) was a predictor of visibility of calcifications by CT. Chest thin-section CT may be useful for localization of calcifications in some patients, especially for calcifications that are only visible in one view on the mammography.

Indexed as

Breast DiseasesBreast NeoplasmsCalcinosisBiopsyBreastFemaleHumansMammographyTomography, X-Ray ComputedBreastMammographyMicrocalcificationMultidetector computed tomography

Identifiers

PMID38419107
PMCPMC10902948
OpenAlexW4392291479

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.