Evidence map›Paper›PMID 38419037›Full record

ArticleJournal of neuroinflammation2024

Inhibition of MMP8 effectively alleviates manic-like behavior and reduces neuroinflammation by modulating astrocytic CEBPD.

Tzu-Yun Wang, Eddie Feng-Ju Weng, Yun-Chen Hsu, Lu-Ping Shiu, Teng-Wei Huang, Hsuan-Cheng Wu, Jau-Shyong Hong, Shao-Ming Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroinflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. CEBPD-MMP8 Axis Contributes to Cardiomyocyte Injury in Septic Shock.Applied biochemistry and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Tzu-Yun Wang *Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Eddie Feng-Ju Weng *Neuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.
Yun-Chen HsuNeuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.
Lu-Ping ShiuNeuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.
Teng-Wei HuangNeuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.
Hsuan-Cheng WuNeuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan.
Jau-Shyong HongNeurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T.W. Alexander Dr., Research Triangle Park, Durham, NC, 27709, USA.
Shao-Ming WangNeuroscience and Brain Disease Center, China Medical University, Taichung, Taiwan. wangs@mail.cmu.edu.tw.ORCID http://orcid.org/0000-0003-1479-9100
China Medical University · TWNational Cheng Kung University Hospital · TWNational Institutes of Health · US

Funding

National Science and Technology Council 111-2320-B-039-075National Science and Technology Council MOST 111-2314-B-006-033-MY3National Science and Technology Council MOST 111-2628-B-039-006-MY3National Science and Technology Council NSTC 111-2320-B-039 -073 -MY2
6 · The paper itself

Abstract

There is an intrinsic relationship between psychiatric disorders and neuroinflammation, including bipolar disorder. Ouabain, an inhibitor of Na

Indexed as

Neuroinflammatory DiseasesOuabainAnimalsAstrocytesCCAAT-Enhancer-Binding Protein-deltaHumansMatrix Metalloproteinase 8MiceCCAAT-Enhancer-Binding Protein-deltaCEBPD protein, humanCebpd protein, mouseMatrix Metalloproteinase 8MMP8 protein, humanMMP8 protein, mouseOuabainBipolar diseaseCEBPDMMP8NeuroinflammationOuabain-induced manic-like behavior

Identifiers

PMID38419037
PMCPMC10900742
OpenAlexW4392234165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.