ArticleRespiratory research2024
Associations between long-term ozone exposure and small airways function in Chinese young adults: a longitudinal cohort study.
Article in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Outdoor air pollutants and asthma risk in adolescents: evidence from a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Long-term variability of impulse oscillometry defined small airway dysfunction in participants with and without chronic obstructive pulmonary disease.BMJ open respiratory research · 2026Article
- Summer Temperature Exposure and Blood Metabolomics in Young Adults: A Cross-Sectional Study in Shandong, China.Environment & health (Washington, D.C.) · 2026Article
- InNanomaterials (Basel, Switzerland) · 2025Article
- Article
- Short-Term Effect of Ozone Exposure on Small Airway Function in Adult Asthma Patients with PMToxics · 2025Article
- Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches.Environmental science & technology · 2025Article
- Associations of Ozone Exposure with Serum Biomarkers in Acute Myocardial Infarction Patients in Taiyuan, China: The Mediating Role of Metabolites.Environment & health (Washington, D.C.) · 2025Article
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing evidence is appearing that ozone has adverse effects on health. However, the association between long-term ozone exposure and lung function is still inconclusive.
objectivesTo investigate the associations between long-term exposure to ozone and lung function in Chinese young adults.
methodsWe conducted a prospective cohort study among 1594 college students with a mean age of 19.2 years at baseline in Shandong, China from September 2020 to September 2021. Lung function indicators were measured in September 2020 and September 2021, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), forced expiratory flow at the 25th, 50th, and 75th percentile of the FVC (FEF25, FEF50, and FEF75) and mean flow rate between 25% and 75% of the FVC (FEF25-75) were measured. Daily 10 km×10 km ozone concentrations come from a well-validated data-fusion approach. The time-weighted average concentrations in 12 months before the lung function test were defined as the long-term ozone exposure. The associations between long-term ozone exposure and lung function indicators in Chinese young adults were investigated using a linear mixed effects model, followed by stratified analyses regarding sex, BMI and history of respiratory diseases.
resultsEach interquartile range (IQR) (8.9 µg/m
conclusionLong-term exposure to ambient ozone is associated with impaired small airway indicators in Chinese young adults. Females, participants with BMI ≥ 24 kg/m
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