Evidence map›Paper›PMID 38418974›Full record

ArticleBMC palliative care2024

Feasibility of a physical exercise intervention for patients on a palliative care unit: a critical analysis.

Inken Schwonke, Nils Freitag, Paula Aschendorf, Kerstin Wucharz, Johanna Thieme, Iris Appelmann, Moritz Schumann, Frank Elsner

Open access · goldAbstract read
In one paragraph

Article in BMC palliative care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Inken SchwonkeDepartment of Palliative Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany. inken.schwonke@rwth-aachen.de.
Nils FreitagOlympic Training Centre Berlin, Berlin, Germany.
Paula AschendorfDepartment of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.
Kerstin WucharzDepartment of Physiotherapy, Franziska-Schervier Educational Center, Bethlehem Hospital, Stolberg, Germany.
Johanna ThiemePro Sanum Health and Therapy Center Eifel, Nettersheim, Germany.
Iris AppelmannDepartment of Palliative Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Moritz Schumann *Department of Sports Medicine and Exercise Therapy, Chemnitz University of Technology, Chemnitz, Germany.
Frank Elsner *Department of Palliative Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.
RWTH Aachen University · DEBerlin Centre of Competence for Water · DEChemnitz University of Technology · DEGerman Sport University Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent exercise intervention studies have shown promising results in improving quality of life (QoL) and physical function (PF) in diverse chronic disease and advanced cancer patients. However, the effects of structured exercise in palliative care patients, having different therapeutic needs, lower life expectancies and PFs remain unknown. This study primarily aimed to assess the feasibility of an exercise intervention with follow-up by analysing recruitment numbers, screening procedures, acceptability, preferences, and safety of the exercise intervention as well as retention in follow-up. Our secondary aims related to changes in QoL and PF.

methodsThis study comprised of a one-arm design without a control group. Over 6 months, every in-hospital palliative care unit (PCU) patient was screened for eligibility. Eligible patients were asked to participate in a 2-week exercise intervention consisting of resistance training and/or endurance training with moderate or high intensity based on personal preferences and a 4-week follow-up. Before and after the exercise intervention, QoL and PF were assessed and a qualitative interview after the intervention addressed expectations and experiences of the exercise intervention. For follow-up, patients were provided with information on independent training and after 1 and 4 weeks a QoL assessment and qualitative interview were conducted.

resultsOf 124 patients screened, 10 completed the intervention with an adherence rate of (80 ± 25%), of which 6 patients completed follow-up. Endurance training was the most performed training type and only a few minor adverse events occurred in certain or likely connection to the exercise intervention. While physical QoL and PF measured by arm curl strength and time up and go performance improved, mental QoL and the other PF tests remained unchanged.

conclusionDespite the challenges that were faced in our screening and testing process, that are specific to the palliative patient population with their unique therapeutic requirements and varying mental-/ physical capabilities, we discovered the 2-week exercise intervention to be feasible, safe, and well tolerated by palliative care patients. Moreover, it seems that short-term improvements in QoL and PF are possible. Further full scale studies are required to confirm our findings.

trial registrationThe study was retrospectively registered on 25.01.2022 in the German Clinical Trials Register (DRKS00027861).

Indexed as

Palliative CareQuality of LifeExerciseExercise TherapyFeasibility StudiesHumansExercise trainingPalliative carePhysical functionQuality of lifeSports

Identifiers

PMID38418974
PMCPMC10900709
OpenAlexW4392238991

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.