Evidence map›Paper›PMID 38418926›Full record

ArticleCommunications biology2024

CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells.

Misato Nakanishi-Koakutsu, Kenji Miki, Yuki Naka, Masako Sasaki, Takayuki Wakimizu, Stephanie C Napier, Chikako Okubo, Megumi Narita, Misato Nishikawa, Reo Hata and 5 more

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Misato Nakanishi-KoakutsuCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.ORCID 0000-0001-6205-6024
Kenji MikiCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan. kenjimiki.prime@osaka-u.ac.jp.ORCID 0000-0001-7901-6133
Yuki NakaCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Masako SasakiCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Takayuki WakimizuCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Stephanie C NapierTakeda-CiRA Joint program (T-CiRA), Fujisawa, 251-8555, Japan.
Chikako OkuboCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.ORCID 0000-0001-5562-410X
Megumi NaritaCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.ORCID 0000-0002-8198-4042
Misato NishikawaCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Reo HataCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Kazuhisa ChonabayashiCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.
Akitsu HottaCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.ORCID 0000-0002-2619-7441
Kenichi ImahashiTakeda-CiRA Joint program (T-CiRA), Fujisawa, 251-8555, Japan.
Tomoyuki NishimotoTakeda-CiRA Joint program (T-CiRA), Fujisawa, 251-8555, Japan.
Yoshinori YoshidaCenter for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan. yoshinor@cira.kyoto-u.ac.jp.ORCID 0000-0001-5511-9090

Funding

Fondation Leducq 18CVD05Japan Agency for Medical Research and Development (AMED) JP20bm0104001Japan Agency for Medical Research and Development (AMED) JP21bk0104095Japan Agency for Medical Research and Development (AMED) JP21bm0204003Japan Agency for Medical Research and Development (AMED) JP21bm0804008Japan Agency for Medical Research and Development (AMED) JP21bm0804022Japan Agency for Medical Research and Development (AMED) JP21mk0101189Japan Agency for Medical Research and Development (AMED) JP22mk0101241Japan Agency for Medical Research and Development (AMED) JP22ym0126091Japan Agency for Medical Research and Development (AMED) JP23bm132300Japan Agency for Medical Research and Development (AMED) JP23bm1423011MEXT | Japan Society for the Promotion of Science (JSPS) JP17H04176MEXT | Japan Society for the Promotion of Science (JSPS) JP18K15120MEXT | Japan Society for the Promotion of Science (JSPS) JP18KK0461MEXT | Japan Society for the Promotion of Science (JSPS) JP19K16041MEXT | Japan Society for the Promotion of Science (JSPS) JP 21H02912
6 · The paper itself

Abstract

Current differentiation protocols for human induced pluripotent stem cells (hiPSCs) produce heterogeneous cardiomyocytes (CMs). Although chamber-specific CM selection using cell surface antigens enhances biomedical applications, a cell surface marker that accurately distinguishes between hiPSC-derived atrial CMs (ACMs) and ventricular CMs (VCMs) has not yet been identified. We have developed an approach for obtaining functional hiPSC-ACMs and -VCMs based on CD151 expression. For ACM differentiation, we found that ACMs are enriched in the CD151

Indexed as

Induced Pluripotent Stem CellsCell DifferentiationHeart VentriclesHumansMyocytes, CardiacTetraspanin 24CD151 protein, humanTetraspanin 24

Identifiers

PMID38418926
PMCPMC10901864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.