Evidence map›Paper›PMID 38418885›Full record

ArticleNature2024

Crym-positive striatal astrocytes gate perseverative behaviour.

Matthias Ollivier, Joselyn S Soto, Kay E Linker, Stefanie L Moye, Yasaman Jami-Alahmadi, Anthony E Jones, Ajit S Divakaruni, Riki Kawaguchi, James A Wohlschlegel, Baljit S Khakh

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
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  16. Astrocytes as Therapeutic Targets in Neurodegenerative Disorders.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  17. Review
  18. Astrocytes as Active Participants in Memory.Journal of neurochemistry · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Matthias OllivierDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Joselyn S SotoDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Kay E LinkerDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Stefanie L MoyeDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-9699-5406
Yasaman Jami-AlahmadiDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Anthony E JonesDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-2058-6021
Ajit S DivakaruniDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Riki KawaguchiCenter for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
James A WohlschlegelDepartment of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Baljit S KhakhDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. bkhakh@mednet.ucla.edu.ORCID 0000-0002-0939-1218
University of California, Los Angeles · US

Funding

UCLA IDDRC: Translational CoreP50HD103557 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Michael Gandal · 2020 to 2026
$9.6M
Fundamental astrocyte biology in intact neural circuitsR35NS111583 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Baljit Khakh · 2019 to 2026
$7.9M
New tools to target, identify and characterize astrocytes in the adult nervous systemR01DA047444 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRADINARU, VIVIANA, KHAKH, BALJIT · 2018 to 2020
$3.3M
Understanding How Metabolic Cofactors Control Cell Function and FateR35GM138003 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Ajit Divakaruni · 2020 to 2026
$2.8M
Molecular identity, cellular physiology, and in vivo functions of nucleus accumbens astrocytesF32MH125598 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LINKER, KAY ELIZABETH · 2021 to 2022
$114k
NICHD NIH HHS P50 HD103557NIDA NIH HHS R01 DA047444NIGMS NIH HHS R35 GM138003NIMH NIH HHS F32 MH125598NINDS NIH HHS R35 NS111583
6 · The paper itself

Abstract

Astrocytes are heterogeneous glial cells of the central nervous system

Indexed as

AstrocytesCorpus Striatummu-CrystallinsRumination, CognitiveAnimalsCRISPR-Cas SystemsGene EditingGene Knockout TechniquesHumansMedium Spiny NeuronsMiceNeural InhibitionPrefrontal CortexPresynaptic TerminalsSynapsesSynaptic TransmissionCRYM protein, humanCrym protein, mousemu-Crystallins

Identifiers

PMID38418885
PMCPMC10937394
OpenAlexW4392228819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.