Evidence map›Paper›PMID 38418754›Full record

SynthesisJournal of cancer survivorship : research and practice2025

Prevalence, severity, and risk factors of cancer-related fatigue among working cancer survivors: a systematic review and meta-analysis.

Masaaki Matsunaga, Yupeng He, May Thet Khine, Xuliang Shi, Ryusei Okegawa, Yuanying Li, Hiroshi Yatsuya, Atsuhiko Ota

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Systematic review of the needs and health-related quality of life domains relevant to people surviving cancer in Europe.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  3. Trial
  4. Article
  5. Symptom burden in cancer survivorship: insights from a survivorship program's patient-reported outcomes database.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  6. Article
  7. Life beyond remission: physical, emotional, and social reintegration of cancer survivors in Tunisia-a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fatigue in hematological cancer changes across chemotherapy trajectory within the context of IL-6, not hemoglobin level: evidence from growth curve modeling.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Masaaki MatsunagaDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan. mm-223@fujita-hu.ac.jp.
Yupeng HeDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.
May Thet KhineDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.
Xuliang ShiDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.
Ryusei OkegawaDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.
Yuanying LiDepartment of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya, Nagoya, 466-8550, Japan.
Hiroshi YatsuyaDepartment of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya, Nagoya, 466-8550, Japan.
Atsuhiko OtaDepartment of Public Health, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.
Fujita Health University · JPNagoya University · JP

Funding

Japan Society for the Promotion of Science JP22K17403
6 · The paper itself

Abstract

purposeThe aim of this study is to evaluate the prevalence, severity, and risk factors of cancer-related fatigue among currently working cancer survivors.

methodsWe searched the PubMed, Embase, Scopus, CINAHL, Cochrane Library, and ICHUSHI databases. The risk of bias was evaluated independently using the Risk of Bias Assessment Tool for Non-randomized Studies (RoBANS). A meta-analysis was conducted to determine the prevalence, severity, and related factors associated with cancer-related fatigue among currently working cancer survivors.

resultsOur meta-analysis included 18 studies and revealed that 42.2% of currently working cancer survivors experience cancer-related fatigue. The fatigue severity in this group was significantly higher than that in workers without cancer (absolute standardized mean difference (SMD) = 0.67), but lower than that in cancer survivors who had previously worked and were not currently working (absolute SMD = 0.72). Distress was identified as a potential risk factor for cancer-related fatigue in working cancer survivors (partial correlation coefficient = 0.38).

conclusionsThe high prevalence of cancer-related fatigue among employed cancer survivors underscores the need for targeted workplace interventions and fatigue management strategies. While the severity of fatigue is less than that seen in non-working survivors, the comparison with the general working population highlights a significant health disparity. The association between distress and fatigue suggests the necessity for a holistic approach to fatigue management that considers both physical and mental factors in working cancer survivors. IMPLICATIONS FOR CANCER SURVIVORS: Our findings highlight the critical need for healthcare professionals and employers to monitor fatigue levels among working cancer survivors and offer appropriate support.

Indexed as

Cancer SurvivorsFatigueNeoplasmsHumansPrevalenceRisk FactorsSeverity of Illness IndexCancer-related fatigueMeta-analysisPrevalenceRisk factorsSeverityWorkWork retention

Identifiers

PMID38418754
OpenAlexW4392243989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.