Evidence map›Paper›PMID 38418651›Full record

ArticleScientific reports2024

Long-term monitoring of gastric mucosa-associated lymphoid tissue lymphoma in patients with extra copies of the MALT1 gene.

Masaya Iwamuro, Ryuta Takenaka, Koji Miyahara, Shotaro Okanoue, Masao Yoshioka, Chihiro Sakaguchi, Kumiko Yamamoto, Yoshinari Kawai, Tatsuya Toyokawa, Takehiro Tanaka and 1 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. [Endoscopic characteristics of primary gastric lymphoma and prediction of treatment response].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 1 country.

Masaya IwamuroDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan. pr145h2k@okayama-u.ac.jp.
Ryuta TakenakaDepartment of Internal Medicine, Tsuyama Chuo Hospital, Tsuyama, 708‑0841, Japan.
Koji MiyaharaDepartment of Internal Medicine, Hiroshima City Hospital, Hiroshima, 730-8518, Japan.
Shotaro OkanoueDepartment of Gastroenterology, Mitoyo General Hospital, Kanonji, 769‑1695, Japan.
Masao YoshiokaDepartment of Internal Medicine, Okayama Saiseikai General Hospital, Okayama, 700‑8511, Japan.
Chihiro SakaguchiDepartment of Gastroenterology, Shikoku Cancer Center, Matsuyama, 791-0280, Japan.
Kumiko YamamotoDepartment of Gastroenterology, Kagawa Prefectural Central Hospital, Takamatsu, 760‑8557, Japan.
Yoshinari KawaiDepartment of Gastroenterology, Onomichi Municipal Hospital, Onomichi, 722‑8503, Japan.
Tatsuya ToyokawaDepartment of Gastroenterology, Fukuyama Medical Center, Fukuyama, 720‑8520, Japan.
Takehiro TanakaDepartment of Pathology, Okayama University Hospital, Okayama, 700-8558, Japan.
Motoyuki OtsukaDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.
Okayama University · JPFukuyama University · JPHiroshima Prefectural Hospital · JPKagawa Prefectural Central Hospital · JPMito Saiseikai General Hospital · JPOkayama Saiseikai General Hospital · JPOkayama University Hospital · JPOnomichi General Hospital · JPShikoku Cancer Center · JPTsuyama Chuo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to clarify the long-term prognosis of patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma with additional copies of MALT1. In this multicenter retrospective study, we enrolled 145 patients with gastric MALT lymphoma who underwent fluorescence in situ hybridization (FISH) analysis to detect t(11;18) translocation. The patient cohort was divided into three groups: Group A (n = 87), comprising individuals devoid of the t(11;18) translocation or extra MALT1 copies; Group B (n = 27), encompassing patients characterized by the presence of the t(11;18) translocation; and Group C (n = 31), including patients with extra MALT1 copies. The clinical outcomes in each cohort were collected. Over the course of a mean follow-up of 8.5 ± 4.2 years, one patient died of progressive MALT lymphoma, while 15 patients died due to etiologies unrelated to lymphoma. The progression or relapse of MALT lymphoma was observed in 11 patients: three in Group A, two in Group B, and six in Group C. In Groups A, B, and C, the 10-year overall survival rates were 82.5%, 93.8%, and 86.4%, respectively, and the 10-year event-free survival rates were 96.1%, 96.0%, and 82.9%, respectively. The event-free survival rate in Group C was significantly lower than that in Group A. However, no differences were observed in the 10-year event-free survival rates among individuals limited to stage I or II

Indexed as

Lymphoma, B-Cell, Marginal ZoneLymphoma, Non-HodgkinStomach NeoplasmsHumansIn Situ Hybridization, FluorescenceMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinNeoplasm Recurrence, LocalRetrospective StudiesTranslocation, GeneticMALT1 protein, humanMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinEsophagogastroduodenoscopyExtranodal marginal zone lymphoma of mucosa-associated lymphoid tissueGastric neoplasmst(11;18) translocationTrisomy 18

Identifiers

PMID38418651
PMCPMC10902346
OpenAlexW4392770258

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.