Evidence map›Paper›PMID 38418582›Full record

ReviewAdvances in biochemical engineering/biotechnology2025

Mixed Culture Cultivation in Microbial Bioprocesses.

Manisha Khedkar, Dattatray Bedade, Rekha S Singhal, Sandip B Bankar

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Advances in biochemical engineering/biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Manisha Khedkar *MIT School of Bioengineering Sciences & Research, MIT ADT University, Pune, India.
Dattatray Bedade *R & D Laboratories, S K Biobiz Pvt. Ltd., Nasik, India.
Rekha S SinghalDepartment of Food Engineering and Technology, Institute of Chemical Technology, Mumbai, India. rs.singhal@ictmumbai.edu.in.
Sandip B BankarDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Aalto, Finland. sandip.bankar@aalto.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed culture cultivation is well renowned for industrial applications due to its technological and economic benefits in bioprocess, food processing, and pharmaceutical industries. A mixed consortium encompasses to achieve growth in unsterile conditions, robustness to environmental stresses, perform difficult functions, show better substrate utilization, and increase productivity. Hence, mixed cultures are being valorized currently and has also augmented our understanding of microbial activities in communities. This chapter covers a wide range of discussion on recent improvements in mixed culture cultivation for microbial bioprocessing and multifarious applications in different areas. The history of microbial culture, microbial metabolism in mixed culture, biosynthetic pathway studies, isolation and identification of strains, along with the types of microbial interactions involved during their production and propagation, are meticulously detailed in the current chapter. Besides, parameters for evaluating mixed culture performance, large-scale production, and challenges associated with it are also discussed vividly. Microbial community, characteristics of single and mixed culture fermentation, and microbe-microbe interactions in mixed cultures have been summarized comprehensively. Lastly, various challenges and opportunities in the area of microbial mixed culture that are obligatory to improve the current knowledge of microbial bioprocesses are projected.

Indexed as

BacteriaBioreactorsIndustrial MicrobiologyMicrobial ConsortiaCoculture TechniquesFermentationBioprocessFermentationIsolationMetabolismMicrobe-microbe interactionsMixed culture

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.