ArticleCommunications biology2024
Linking structural and functional changes during aging using multilayer brain network analysis.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Structure-function coupling of large-scale cortical networks across the lifespan is spectrally specific.Communications biology · 2026Article
- Brain maintenance biomarkers from structural and functional interactions in aging and neurodegeneration.Nature communications · 2026Article
- Boron as a Molecular Architect of Host-Microbiome Symbiosis: Implications for Dysbiosis and Aging-Related Pathologies.Life (Basel, Switzerland) · 2026Review
- Developmental and aging changes in brain network switching dynamics revealed by EEG phase synchronization.PLoS computational biology · 2026Article
- Hierarchical Flows of Human Cortical Activity.bioRxiv : the preprint server for biology · 2026Article
- Fifteen years on: a review of the Cam-CAN study of the cognitive neuroscience of ageing.GeroScience · 2026Review
- The World Health Organization Integrated Care for Older People (ICOPE) Framework and the Association with Frailty in Older Adults.Annals of geriatric medicine and research · 2026Article
- Longitudinal analysis of hippocampal subfield atrophy and network centrality associated with cognitive decline in Alzheimer's disease progression.Medical physics · 2026Article
- Frequency-Resolved Cortical Functional Connectivity Across the Adult Lifespan.Human brain mapping · 2026Article
- Frequency-resolved cortical functional connectivity across the adult lifespan.bioRxiv : the preprint server for biology · 2026Article
- Impact of tractogram filtering and graph creation for structural connectomics in subjects with Parkinson's disease.Frontiers in human neuroscience · 2026Article
- Cancer and Aging Biomarkers: Classification, Early Detection Technologies and Emerging Research Trends.Biosensors · 2025Review
- Age-related constraints on the spatial geometry of the brain.Nature communications · 2025Article
- Aging diminishes interlaminar functional connectivity in the mouse cortical V1 and CA1 hippocampal regions.bioRxiv : the preprint server for biology · 2025Article
- Linking Individual Variability of Multi-modal Connectivity, Lifestyle, Psycho-Social Factors and Cognition in Older Adults.Aging and disease · 2025Article
- The balance between integration and segregation drives network dynamics maximizing multistability and metastability.Scientific reports · 2025Article
- Reduced parietal to frontal functional connectivity for dynamic balance in late middle-to-older adults.Experimental brain research · 2025Article
- CLASSIFFICATION OF MILD COGNITIVE IMPAIRMENT BASED ON DYNAMIC FUNCTIONAL CONNECTIVITY USING SPATIO-TEMPORAL TRANSFORMER.Proceedings. IEEE International Symposium on Biomedical Imaging · 2025Article
- Topological Biomarkers of Alzheimer's Disease from Functional Brain Network Analysis.Current Alzheimer research · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
Brain structure and function are intimately linked, however this association remains poorly understood and the complexity of this relationship has remained understudied. Healthy aging is characterised by heterogenous levels of structural integrity changes that influence functional network dynamics. Here, we use the multilayer brain network analysis on structural (diffusion weighted imaging) and functional (magnetoencephalography) data from the Cam-CAN database. We found that the level of similarity of connectivity patterns between brain structure and function in the parietal and temporal regions (alpha frequency band) is associated with cognitive performance in healthy older individuals. These results highlight the impact of structural connectivity changes on the reorganisation of functional connectivity associated with the preservation of cognitive function, and provide a mechanistic understanding of the concepts of brain maintenance and compensation with aging. Investigation of the link between structure and function could thus represent a new marker of individual variability, and of pathological changes.
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