Evidence map›Paper›PMID 38418208›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2024

Factors that impact second attempt success for neonatal intubation following first attempt failure: a report from the National Emergency Airway Registry for Neonates.

Mitchell David Johnson, David Gerald Tingay, Elizabeth J Perkins, Arun Sett, Bianca Devsam, Ellen Douglas, Julia K Charlton, Paul Wildenhain, Jennifer Rumpel, Michael Wagner and 14 more

Open access · greenAbstract read
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 16 institutions in 5 countries.

Mitchell David JohnsonNeonatal Medicine, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia mitchell.johnson@rch.org.au.ORCID http://orcid.org/0000-0001-6139-7476
David Gerald TingayNeonatal Medicine, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-1522-4691
Elizabeth J PerkinsNeonatal Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Arun SettNeonatal Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Bianca DevsamNeonatal Medicine, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.
Ellen DouglasNeonatal Research, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Julia K CharltonDepartment of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.
Paul WildenhainThe Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Jennifer RumpelDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Michael WagnerDivision of Neonatology, Pediatric Intensive Care and Neuropediatrics, Department of Pediatrics, Medical University Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0003-0982-2310
Vinay NadkarniDepartment of Anesthesiology, Critical Care, and Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Lindsay JohnstonDepartment of Pediatrics, Yale University, New Haven, Connecticut, USA.
Heidi M HerrickDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Tyler HartmanDepartment of Pediatrics, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Kristen GlassDepartment of Pediatrics, Penn State Health Children's Hospital/Penn State College of Medicine, Hershey, Pennsylvania, USA.
Philipp JungDepartment of Pediatrics, University Hospital Schleswig-Holstein, Luebeck, Germany.
Stephen D DeMeoDivision of Neonatology, WakeMed Health and Hospitals, Raleigh, North Carolina, USA.
Rebecca ShayDepartment of Pediatrics, Division of Neonatology, University of Colorado, Aurora, Colorado, USA.
Jae H KimPerinatal Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Jennifer UnrauNewborn Critical Care, Alberta Children's Hospital, Calgary, Alberta, Canada.
Ahmed MoussaDivision of Neonatology, Department of Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada.
Akira NishisakiDepartment of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Elizabeth E FogliaDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
National Emergency Airway Registry for Neonates (NEAR4NEOS) investigators
Children's Hospital of Philadelphia · USRoyal Children's Hospital · AUMurdoch Children's Research Institute · AUAlberta Children's Hospital · CACentre Hospitalier Universitaire Sainte-Justine · CACincinnati Children's Hospital Medical Center · USDartmouth–Hitchcock Medical Center · USMedical University of Vienna · ATPenn State Milton S. Hershey Medical Center · USThe University of Melbourne · AUUniversity Hospital Schleswig-Holstein · DEUniversity of Arkansas for Medical Sciences · USUniversity of Colorado Anschutz Medical Campus · USWakeMed · USWestern Health · AUYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Optimizing Tracheal Intubation Outcomes and Neonatal Safety (OPTION SAFE)R01HD106996 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Elizabeth Foglia · 2022 to 2026
$3.6M
Leveraging Human Factors to Evaluate Quality of Neonatal Delivery Room CareK08HS029029 · AHRQ · CHILDREN'S HOSP OF PHILADELPHIA · PI Heidi Herrick · 2022 to 2026
$713k
AHRQ HHS K08 HS029029NCATS NIH HHS UL1 TR001863NICHD NIH HHS R01 HD106996
6 · The paper itself

Abstract

objectiveTo determine the factors associated with second attempt success and the risk of adverse events following a failed first attempt at neonatal tracheal intubation.

designRetrospective analysis of prospectively collected data on intubations performed in the neonatal intensive care unit (NICU) and delivery room from the National Emergency Airway Registry for Neonates (NEAR4NEOS).

settingEighteen academic NICUs in NEAR4NEOS. PATIENTS: Neonates requiring two or more attempts at intubation between October 2014 and December 2021.

main outcome measuresThe primary outcome was successful intubation on the second attempt, with severe tracheal intubation-associated events (TIAEs) or severe desaturation (≥20% decline in oxygen saturation) being secondary outcomes. Multivariate regression examined the associations between these outcomes and patient characteristics and changes in intubation practice.

results5805 of 13 126 (44%) encounters required two or more intubation attempts, with 3156 (54%) successful on the second attempt. Second attempt success was more likely with changes in any of the following: intubator (OR 1.80, 95% CI 1.56 to 2.07), stylet use (OR 1.65, 95% CI 1.36 to 2.01) or endotracheal tube (ETT) size (OR 2.11, 95% CI 1.74 to 2.56). Changes in stylet use were associated with a reduced chance of severe desaturation (OR 0.74, 95% CI 0.61 to 0.90), but changes in intubator, laryngoscope type or ETT size were not; no changes in intubator or equipment were associated with severe TIAEs.

conclusionsSuccessful neonatal intubation on a second attempt was more likely with a change in intubator, stylet use or ETT size.

Indexed as

Intensive Care Units, NeonatalIntubation, IntratrachealRegistriesFemaleHumansInfant, NewbornMaleRetrospective StudiesTreatment FailureIntensive Care Units, NeonatalNeonatologyResuscitation

Identifiers

PMID38418208
PMCPMC11349927
OpenAlexW4392231059

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.