Evidence map›Paper›PMID 38418157›Full record

ArticleIn vivo (Athens, Greece)

Severe Burn Injuries - The Day the Sodium Starts Rising.

Maximilian M Menger, Holger Wenz, Maximilian Bamberg, Sabrina KRAUß, Henrik Lauer, Tim Viergutz, Johann Fontana

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maximilian M MengerDepartment of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, Tuebingen, Germany.
Holger WenzDepartment of Neuroradiology, Medical Faculty Mannheim, University Medical Center Mannheim, University of Heidelberg, Heidelberg, Germany.
Maximilian BambergDepartment of Anesthesiology and Intensive Care Medicine, BG Trauma Center Tuebingen, Tuebingen, Germany.
Sabrina KRAUßDepartment of Hand, Plastic, Reconstructive and Burn Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, Tuebingen, Germany.
Henrik LauerDepartment of Hand, Plastic, Reconstructive and Burn Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, Tuebingen, Germany.
Tim ViergutzDepartment of Anesthesiology and Intensive Care Medicine, BG Trauma Center Tuebingen, Tuebingen, Germany.
Johann FontanaDepartment of Anesthesiology and Intensive Care Medicine, BG Trauma Center Tuebingen, Tuebingen, Germany; jfontana@bgu-tuebingen.de.
University of Tübingen · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe current study was designed to evaluate the etiologies of hypernatremic episodes in patients with severe burn injuries in comparison to critically ill non-burn patients. PATIENTS AND

methodsThe retrospective data acquisition was limited to the first 14 days and to patients with at least 20% total body surface area (TBSA) 2

resultsIn total, 120 patients with a total of 50 hypernatremic episodes were included. Compared to non-burn injury patients, no significant differences were detectable except for a lower rate of hypokalemia and a higher rate of mechanical ventilation. The main trigger for hypernatremic episodes was the loss of free water, while 24% of the hypernatremic episodes seemed to be at least partly triggered by a surplus sodium influx. Patients with hypernatremic episodes had a significantly higher mortality rate. However, in none of the cases was hypernatremia the decisive cause of death.

conclusionBesides the unique phenomenon of high volume internal and external volume shifts, the overall risk factors and etiologies of hypernatremia in patients with severe burn injury do not seem to significantly differ from other ICU patient collectives. Remarkably, a surplus of sodium influx and therefore a modifiable factor besides the specific burn injury volume resuscitation had an impact on the hypernatremic episodes in 24% of cases.

Indexed as

HypernatremiaSodiumHumansIntensive Care UnitsRetrospective StudiesRisk FactorsSodiumBurn injuryhypernatremiarisk factorssodium

Identifiers

PMID38418157
PMCPMC10905458
OpenAlexW4392250806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.