Evidence map›Paper›PMID 38417928›Full record

ArticleBMJ paediatrics open2024

Assessment of the role of gut health in childhood stunting in a multisite, longitudinal study in India, Indonesia and Senegal: a UKRI GCRF Action Against Stunting Hub protocol.

Benjamin Momo Kadia, Anouschka S Ramsteijn, Teena Dasi, Umi Fahmida, Bharati Kulkarni, Babacar Faye, Min Kyaw Htet, Doudou Sow, Rajender Rao Kalashikam, Ritu Sharma and 14 more

Open access · diamondAbstract read
In one paragraph

Article in BMJ paediatrics open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 6 countries.

Benjamin Momo KadiaDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK benjamin.kadia@lstmed.ac.uk.ORCID 0000-0002-8566-7132
Anouschka S RamsteijnRowett Institute, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-7269-1707
Teena DasiICMR-National Institute of Nutrition, Hyderabad, India.
Umi FahmidaSoutheast Asian Ministry of Education Organisation Regional Centre for Food and Nutrition (SEAMEO RECFON), East Jakarta, Indonesia.ORCID 0000-0003-1403-6242
Bharati KulkarniICMR-National Institute of Nutrition, Hyderabad, India.ORCID 0000-0003-0636-318X
Babacar FayeService de Parasitologie-Mycologie, Faculté de Médecine, Université Cheikh Anta Diop (UCAD), Dakar, Sénégal.ORCID 0000-0001-8022-4335
Min Kyaw HtetSoutheast Asian Ministry of Education Organisation Regional Centre for Food and Nutrition (SEAMEO RECFON), East Jakarta, Indonesia.ORCID 0000-0001-6417-2942
Doudou SowService de Parasitologie-Mycologie, UFR Sciences de la Santé, Université Gaston Berger, Saint Louis, Sénégal.ORCID 0000-0002-0560-2372
Rajender Rao KalashikamICMR-National Institute of Nutrition, Hyderabad, India.ORCID 0000-0003-4492-3651
Ritu SharmaICMR-National Institute of Nutrition, Hyderabad, India.
Arienta R P SudibyaSoutheast Asian Ministry of Education Organisation Regional Centre for Food and Nutrition (SEAMEO RECFON), East Jakarta, Indonesia.
Sari KusumaSoutheast Asian Ministry of Education Organisation Regional Centre for Food and Nutrition (SEAMEO RECFON), East Jakarta, Indonesia.
Tiffany C AngelinSoutheast Asian Ministry of Education Organisation Regional Centre for Food and Nutrition (SEAMEO RECFON), East Jakarta, Indonesia.ORCID 0000-0003-1338-9409
Mifa NurfadilahSoutheast Asian Ministry of Education Organisation Regional Centre for Food and Nutrition (SEAMEO RECFON), East Jakarta, Indonesia.
Modou Lamin JobartehDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-7350-6980
Ndeye Sokhna DiopService de Parasitologie-Mycologie, Faculté de Médecine, Université Cheikh Anta Diop (UCAD), Dakar, Sénégal.
Isobel GabainDepartment of Pathobiology and Population Sciences, Royal Veterinary College, University of London, London, UK.ORCID 0000-0002-8460-739X
Beatriz Calvo-UrbanoDepartment of Pathobiology and Population Sciences, Royal Veterinary College, University of London, London, UK.ORCID 0000-0002-1059-6843
Elaine FergusonDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0003-4673-5128
Paul HaggartyRowett Institute, University of Aberdeen, Aberdeen, UK.
Claire HeffernanDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Joanne P Webster *Department of Pathobiology and Population Sciences, Royal Veterinary College, University of London, London, UK.ORCID 0000-0001-8616-4919
Alan W Walker *Rowett Institute, University of Aberdeen, Aberdeen, UK.ORCID 0000-0001-5099-8495
Stephen Allen *Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.ORCID 0000-0001-6675-249X
SEAMEO Regional Center for Food and Nutrition · IDNational Institute of Nutrition · INUniversity of Aberdeen · GBUniversity of London · GBLiverpool School of Tropical Medicine · GBLondon School of Hygiene & Tropical Medicine · GBService de la Santé Publique · CHLondon International Development Centre · GBUniversité Gaston Berger · SN

Funding

Medical Research Council MR/S01313X/1
6 · The paper itself

Abstract

introductionChildhood stunting has a complex aetiology, with poor gut health being an important contributor. This study will assess inter-relationships between maternal and infant gut health indices and infant linear growth. Inter-relationships between gut health indices, systemic inflammation and growth hormones in early childhood will also be assessed. METHODS AND ANALYSIS: A longitudinal observational study of cohorts of 600 newborns and their mothers in India, Indonesia and Senegal will be conducted. Women will be recruited during pregnancy and their children followed up to age 24 months. Stool, urine and blood samples will be collected from the women and children for assessments of helminthic and protozoal parasites, bacterial pathogens, faecal microbiota taxa, biomarkers of environmental enteric dysfunction, systemic inflammation and growth hormones. Child anthropometric measurements will be collected at birth and at ages 3, 6, 9, 12, 18 and 24 months. The gut health indices will be integrated with cohort data from other Action Against Stunting Hub (AASH) workstreams for interdisciplinary analyses of childhood stunting and the development of a new typology of stunting. DISCUSSION: This study will advance scientific understanding of the role of gut health in childhood stunting and will contribute to a broader knowledge of the complex aetiology of this condition as part of the interdisciplinary AASH research to reduce the global burden of childhood stunting. ETHICS AND DISSEMINATION: This study has been approved by the relevant Ethics Committees in Senegal, India, and Indonesia and LSHTM. The results will be submitted for publication in peer-reviewed journals.

Indexed as

Growth DisordersMothersChildChild, PreschoolFemaleHormonesHumansIndonesiaInfantInfant, NewbornInflammationLongitudinal StudiesObservational Studies as TopicPregnancySenegalHormonesgastroenterologygrowthmicrobiologymolecular biologyparasitology

Identifiers

PMID38417928
PMCPMC10900321
OpenAlexW4392244711

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.