Evidence map›Paper›PMID 38417133›Full record

ArticleJournal of the Chinese Medical Association : JCMA2024

Risk factors associated with hepatitis D virus infection and preventive strategies in Mongolia.

Chien-Wei Su, Bayarmaa Ochirkhuree, Bira Namdag, Batsukh Badamnachin, Sarangua Ganbold, Sarantuya Gidaagaya, Anar Ganbold, Sien-Sing Yang, Davaadorj Duger, Jaw-Ching Wu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Chinese Medical Association : JCMA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Chien-Wei SuDivision of General Medicine, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Bayarmaa OchirkhureeGastroenterology Center, First Central Hospital of Mongolia, Ulaanbaatar, Mongolia.
Bira NamdagDepartment of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Batsukh BadamnachinEmergency Department, National Center for Communicable Disease, Ulaanbaatar, Mongolia.
Sarangua GanboldHepatology Laboratory, National Center for Communicable Diseases, Ulaanbaatar, Mongolia.
Sarantuya GidaagayaDepartment of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Anar GanboldGastroenterology Center, First Central Hospital of Mongolia, Ulaanbaatar, Mongolia.
Sien-Sing YangLiver Unit, Cathay General Hospital, Taipei, Taiwan, ROC.
Davaadorj DugerDepartment of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Jaw-Ching WuInstitute of Clinical Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
Mongolian National University · MNNational Center for Communicable Diseases · MNCathay General Hospital · TWMongolian National University of Medical Sciences · MNNational Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis D virus (HDV) infection is highly prevalent in Mongolia. We aimed to identify the risk factors associated with HDV infection, propose preventive strategies, and evaluate the outcomes of a 3-year collaborative project between Taiwan and Mongolia.

methodsIn 2016 and 2018, we conducted onsite visits to Mongolia. Mongolian investigators collected questionnaires focusing on risk factors, demographic characteristics, and serum samples for acute HDV infections. Furthermore, 19 Mongolian seed teachers participated in a 1-week workshop on infection control in Taiwan. Subsequently, these seed teachers trained more than 400 medical personnel in Mongolia. To assess secular changes in acute HDV infection, we reviewed the registration data from the National Center for Communicable Disease (NCCD) in Mongolia between 2011 and 2021.

resultsAmong the 194 Mongolian patients, 108 had dual infection with hepatitis B virus (HBV) and HDV, while 86 had acute hepatitis B (AHB). Patients with HBV/HDV dual infections were older (28.6 vs 25.5 years, p = 0.030) and had lower rates of positive hepatitis B e antigen in their sera, lower rates of serum HBV DNA exceeding 2000 IU/mL, and higher rates of having received dental treatment (59.4% vs 40.5%, p = 0.014) and injection therapy (64.2% vs 44.0%, p = 0.009) compared with those with AHB. Analysis of NCCD data revealed that new HDV infection cases were more prevalent between 2011 and 2015 (111.20 ± 29.79 cases/y) and decreased to 54.67 ± 27.34 cases/y between 2016 and 2021 ( p = 0.010).

conclusionDental treatment and injections were associated with a higher risk of acute HDV infections in Mongolia. Through collaborative efforts, the incidence rate of HDV infection has declined in recent years.

Indexed as

Hepatitis DAdolescentAdultFemaleHepatitis BHepatitis Delta VirusHumansMaleMiddle AgedMongoliaRisk FactorsYoung Adult

Identifiers

PMID38417133
PMCPMC12718865
OpenAlexW4392229614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.