Acoustic Wave-Induced Stroboscopic Optical Mechanotyping of Adherent Cells.

Thomas Combriat, Petter Angell Olsen, Silja Borring Låstad, Anders Malthe-Sørenssen, Stefan Krauss, Dag Kristian Dysthe

Open access · goldAbstract read

In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Acoustic Wave-Induced Stroboscopic Optical Mechanotyping of Adherent Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Thomas CombriatNjord Centre, Department of Physics, University of Oslo, P.O. Box 1048 Blindern, Oslo, 0316, Norway.ORCID 0000-0001-7991-3774

Petter Angell OlsenHybrid Technology Hub, University of Oslo, Institute of Basic Medical Sciences P.O. Box 1110 Blindern, Oslo, 0317, Norway.ORCID 0000-0001-6976-5472

Silja Borring LåstadNjord Centre, Department of Physics, University of Oslo, P.O. Box 1048 Blindern, Oslo, 0316, Norway.

Anders Malthe-SørenssenNjord Centre, Department of Physics, University of Oslo, P.O. Box 1048 Blindern, Oslo, 0316, Norway.

Stefan KraussHybrid Technology Hub, University of Oslo, Institute of Basic Medical Sciences P.O. Box 1110 Blindern, Oslo, 0317, Norway.ORCID 0000-0001-6992-8091

Dag Kristian DystheNjord Centre, Department of Physics, University of Oslo, P.O. Box 1048 Blindern, Oslo, 0316, Norway.ORCID 0000-0001-8336-5061

Norwegian Computing Center · NOOslo University Hospital · NOUniversity of Oslo · NO

Funding

Livsvitenskap, Universitetet i Oslo: ABINONorges Forskningsråd 262613

6 · The paper itself

Abstract

In this study, a novel, high content technique using a cylindrical acoustic transducer, stroboscopic fast imaging, and homodyne detection to recover the mechanical properties (dynamic shear modulus) of living adherent cells at low ultrasonic frequencies is presented. By analyzing the micro-oscillations of cells, whole populations are simultaneously mechanotyped with sub-cellular resolution. The technique can be combined with standard fluorescence imaging allowing to further cross-correlate biological and mechanical information. The potential of the technique is demonstrated by mechanotyping co-cultures of different cell types with significantly different mechanical properties.

Indexed as

StroboscopyAnimalsCell AdhesionHumansOptical ImagingSoundbiophysicscell mechanicslive cell imagingultrasoundviscoelasticity

Identifiers

PMID38417124

DOI10.1002/advs.202307929

PMCPMC11040383

OpenAlexW4392229696

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.