Evidence map›Paper›PMID 38416829›Full record

ArticleScience advances2024

Cryo-EM analysis of

Franco K K Li, Liam J Worrall, Robert T Gale, Eric D Brown, Natalie C J Strynadka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. D-Serine Can Modify the Wall Teichoic Acid of MRSA via theInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Franco K K LiDepartment of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-7318-9754
Liam J WorrallDepartment of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, Canada.
Robert T GaleDepartment of Biochemistry and Biomedical Sciences, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.
Eric D BrownDepartment of Biochemistry and Biomedical Sciences, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-7624-8112
Natalie C J StrynadkaDepartment of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-4058-9425
University of British Columbia · CAMcMaster University · CA

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
Howard Hughes Medical InstituteNIGMS NIH HHS P30 GM124169NIGMS NIH HHS U24 GM129547
6 · The paper itself

Abstract

Wall teichoic acid (WTA), a covalent adduct of Gram-positive bacterial cell wall peptidoglycan, contributes directly to virulence and antibiotic resistance in pathogenic species. Polymerization of the

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcus aureusCryoelectron MicroscopyDrug Resistance, MicrobialPhosphatesRibitolTeichoic AcidsVirulencePhosphatesRibitolTeichoic Acids

Identifiers

PMID38416829
PMCPMC10901376
OpenAlexW4392265956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.