Evidence map›Paper›PMID 38416659›Full record

SynthesisRespiratory care2024

The Impact of Positive Expiratory Pressure Therapy on Hyperinflation in Patients With COPD.

Juliana Ribeiro Fonseca Franco de Macedo, Elinaldo da Conceiçãodos Dos Santos, Gregory Reychler, William Poncin

Open access · greenAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Respiratory care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Juliana Ribeiro Fonseca Franco de MacedoMs Franco de Macedo and Drs Reychler and Poncin are affiliated with Institute de Recherche Expérimentale et Clinique, Pôle de Pneumologie, ORL and Dermatologie, Université Catholique de Louvain, 1200 Brussels, Belgium; Service de Pneumologie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium; and Secteur de Kinésithérapie et Ergothérapie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium. Dr Conceição dos Santos is affiliated with Department of Biological and Health Sciences. Universidade Federal do Amapá, Macapá, Brazil.
Elinaldo da Conceiçãodos Dos SantosMs Franco de Macedo and Drs Reychler and Poncin are affiliated with Institute de Recherche Expérimentale et Clinique, Pôle de Pneumologie, ORL and Dermatologie, Université Catholique de Louvain, 1200 Brussels, Belgium; Service de Pneumologie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium; and Secteur de Kinésithérapie et Ergothérapie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium. Dr Conceição dos Santos is affiliated with Department of Biological and Health Sciences. Universidade Federal do Amapá, Macapá, Brazil.
Gregory ReychlerMs Franco de Macedo and Drs Reychler and Poncin are affiliated with Institute de Recherche Expérimentale et Clinique, Pôle de Pneumologie, ORL and Dermatologie, Université Catholique de Louvain, 1200 Brussels, Belgium; Service de Pneumologie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium; and Secteur de Kinésithérapie et Ergothérapie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium. Dr Conceição dos Santos is affiliated with Department of Biological and Health Sciences. Universidade Federal do Amapá, Macapá, Brazil.
William PoncinMs Franco de Macedo and Drs Reychler and Poncin are affiliated with Institute de Recherche Expérimentale et Clinique, Pôle de Pneumologie, ORL and Dermatologie, Université Catholique de Louvain, 1200 Brussels, Belgium; Service de Pneumologie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium; and Secteur de Kinésithérapie et Ergothérapie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium. Dr Conceição dos Santos is affiliated with Department of Biological and Health Sciences. Universidade Federal do Amapá, Macapá, Brazil. william.poncin@uclouvain.be.
Cliniques Universitaires Saint-Luc · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung hyperinflation is a typical clinical feature of patients with COPD. Given the association between breathing at elevated lung volumes and the manifestation of severe debilitating symptoms, therapeutic interventions such as positive expiratory pressure (PEP) therapy and its variations (temporary, oscillatory) have been devised to mitigate lung hyperinflation. However, the efficacy of these interventions remains to be conclusively demonstrated.

methodsA systematic review with meta-analysis of randomized trials was conducted following the PRISMA guidelines. Seven databases were screened with no date or language restriction. Two authors independently applied eligibility criteria and assessed the risk of bias of included studies using the Cochrane risk-of-bias tool. Outcomes were lung hyperinflation measures detected through changes in inspiratory capacity (IC), functional residual capacity (FRC), total lung capacity (TLC), and residual volume (RV), as well as FEV

resultsSeven trials, all with a high risk of bias, were included. Compared to control group, RV significantly decreased (4 studies,

conclusionsIn patients with COPD, the effect of PEP therapy on lung hyperinflation is unclear owing to the non-consistent change in lung hyperinflation outcomes, insufficient data, and lack of high-quality trials. Dyspnea and physical capacity might improve with PEP therapy.

Indexed as

Positive-Pressure RespirationPulmonary Disease, Chronic ObstructiveResidual VolumeDyspneaFemaleForced Expiratory VolumeFunctional Residual CapacityHumansInspiratory CapacityLungMaleRandomized Controlled Trials as TopicTotal Lung CapacityTreatment OutcomeVital CapacityCOPDhyperinflationpositive expiratory pressuresystematic review

Identifiers

PMID38416659
PMCPMC10984590
OpenAlexW4392233785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.