Evidence map›Paper›PMID 38416349›Full record

ArticleInternational journal of clinical pharmacy2024

Unveiling the future: precision pharmacovigilance in the era of personalized medicine.

Lurdes Silva, Teresa Pacheco, Emília Araújo, Rita J Duarte, Inês Ribeiro-Vaz, Renato Ferreira-da-Silva

Abstract read
In one paragraph

Article in International journal of clinical pharmacy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lurdes SilvaFaculty of Pharmacy of the University of Porto, Porto, Portugal.
Teresa PachecoFaculty of Pharmacy of the University of Porto, Porto, Portugal.
Emília AraújoPalliative Care Service, Portuguese Oncology Institute of Porto (IPO Porto), Porto, Portugal.
Rita J DuartePharmacovigilance, Bayer Portugal, Lisbon, Portugal.
Inês Ribeiro-VazCenter for Health Technology and Services Research, Associate Laboratory RISE - Health Research Network (CINTESIS@RISE), Porto, Portugal.
Renato Ferreira-da-SilvaCenter for Health Technology and Services Research, Associate Laboratory RISE - Health Research Network (CINTESIS@RISE), Porto, Portugal. renato.ivos@gmail.com.ORCID http://orcid.org/0000-0001-6517-6021

Funding

Fundação para a Ciência e a Tecnologia 2020.10231.BD
6 · The paper itself

Abstract

In the era of personalized medicine, pharmacovigilance faces new challenges and opportunities, demanding a shift from traditional approaches. This article delves into the evolving landscape of drug safety monitoring in the context of personalized treatments. We aim to provide a succinct reflection on the intersection of tailored therapeutic strategies and vigilant pharmacovigilance practices. We discuss the integration of pharmacogenetics in enhancing drug safety, illustrating how genetic profiling aids in predicting drug responses and adverse reactions. Emphasizing the importance of phase IV-post-marketing surveillance, we explore the limitations of pre-marketing trials and the necessity for a comprehensive approach to drug safety. The article discusses the pivotal role of pharmacogenetics in pre-exposure risk management and the redefinition of pharmacoepidemiological methods for post-exposure surveillance. We highlight the significance of integrating patient-specific genetic profiles in creating personalized medication leaflets and the use of advanced computational methods in data analysis. Additionally, we examine the ethical, privacy, and data security challenges inherent in precision medicine, emphasizing their implications for patient consent and data management.

Indexed as

Drug-Related Side Effects and Adverse ReactionsPharmacogeneticsPharmacovigilancePrecision MedicineHumansProduct Surveillance, PostmarketingDrug safetyPatient outcomesPersonalized medicinePharmacogenomicsPharmacovigilancePrecision medicine

Identifiers

PMID38416349
PMCPMC11133017

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.