Evidence map›Paper›PMID 38415646›Full record

ArticlemBio2024

Increased production of aureolysin and staphopain A is a primary determinant of the reduced virulence of

Mara J Campbell, Karen E Beenken, Aura M Ramirez, Mark S Smeltzer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Osteomyelitis.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. The secreted proteasesVirulence · 2025
    Article
  6. Article
  7. Microorganisms · 2025
    Review
  8. The ability ofInfection and immunity · 2025
    Article
  9. Microorganisms · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mara J CampbellDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-5131-8129
Karen E BeenkenDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Aura M RamirezDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Mark S SmeltzerDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-0878-0692
University of Arkansas for Medical Sciences · US

Funding

Pilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MARK S SMELTZER · 2022 to 2026
$7.6M
Impact of Staphylococcus aureus in osteomyelitis and bone physiologyR01AI119380 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BEENKEN, KAREN E., SMELTZER, MARK S · 2015 to 2025
$4.1M
NIAID NIH HHS R01 AI119380NIGMS NIH HHS P30 GM145393
6 · The paper itself

Abstract

We previously demonstrated that mutation of

Indexed as

MetalloendopeptidasesOsteomyelitisStaphylococcal InfectionsAnimalsBacterial ProteinsBiofilmsDisease Models, AnimalGene Expression Regulation, BacterialHumansMammalsMethicillinMicePeptide HydrolasesStaphylococcus aureusVirulenceVirulence FactorsaureolysinBacterial ProteinsMetalloendopeptidasesMethicillinPeptide HydrolasesVirulence FactorsbiofilmcytotoxicityosteomyelitisproteasessarAStaphylococcus aureus

Identifiers

PMID38415646
PMCPMC11005355
OpenAlexW4392232201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.