Evidence map›Paper›PMID 38415594›Full record

ArticlemBio2024

Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen

Curtis B Read, Anika N Ali, Daniel J Stephenson, H Patrick Macknight, Kenneth D Maus, Chelsea L Cockburn, Minjung Kim, Xiujie Xie, Jason A Carlyon, Charles E Chalfant

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of Ceramide Kinase/C1P in the Regulation of Cell Growth and Survival.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Identification of theFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Curtis B Read *Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, Virginia, USA.
Anika N Ali *Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Daniel J StephensonDivision of Hematology & Oncology, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.
H Patrick MacknightDivision of Hematology & Oncology, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Kenneth D MausDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Chelsea L CockburnDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, Virginia, USA.
Minjung KimDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Xiujie XieDivision of Hematology & Oncology, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.
Jason A CarlyonDepartment of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, Virginia, USA.ORCID 0000-0003-2778-5066
Charles E ChalfantDivision of Hematology & Oncology, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-5844-5235
University of South Florida · USUniversity of Virginia · USVirginia Commonwealth University Medical Center · USUnited States Department of Veterans Affairs · US

Funding

The roles of ceramide and its derivatives in A. phagocytophilum pathogenesisR01AI139072 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CHARLES E. CHALFANT, Jason A Carlyon · 2018 to 2026
$5.7M
The roles of Anaplasma phagocytophilum surface proteins in infectionR37AI072683 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI Jason A Carlyon · 2022 to 2026
$2.6M
iPLA2beta-mediated alternative splicing and -cell death in type 1 diabetesR01DK126444 · NIDDK · UNIVERSITY OF VIRGINIA · PI CHALFANT, CHARLES E., EIZIRIK, DECIO LAKS · 2021 to 2024
$2.0M
The role of ceramide kinase in mitophagyR01GM137578 · NIGMS · UNIVERSITY OF VIRGINIA · PI CHALFANT, CHARLES E. · 2020 to 2023
$1.3M
The role of RNA splicing in non-small cell lung cancerI01BX001792 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI CHALFANT, CHARLES E. · 2013 to 2024
–
BLRD Research Career Scientist Award ApplicationIK6BX004603 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI CHALFANT, CHARLES E. · 2019 to 2025
–
BLRD VA I01 BX001792BLRD VA I01 BX006063BLRD VA IK6 BX004603NIAID NIH HHS R01 AI139072NIAID NIH HHS R37 AI072683NIDDK NIH HHS R01 DK126444NIGMS NIH HHS R01 GM137578
6 · The paper itself

Abstract

Many intracellular pathogens structurally disrupt the Golgi apparatus as an evolutionarily conserved promicrobial strategy. Yet, the host factors and signaling processes involved are often poorly understood, particularly for

Indexed as

Anaplasma phagocytophilumNeoplasmsAnimalsCeramidesGolgi ApparatusHumansMammalsMiceceramide 1-phosphateCeramidesAnaplasma phagocytophilumceramide-1-phosphateceramide-1-phosphate transport proteinceramide kinaseGolgiGoRASPGRASPhost-pathogen interactionintracellular bacterial pathogen

Identifiers

PMID38415594
PMCPMC11005342
OpenAlexW4392240821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.