Evidence map›Paper›PMID 38415302›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2026

Hyperdense sign as a predictor for successful recanalization and clinical outcome in acute ischemic stroke: A systematic review and meta-analysis.

Khaled Gharaibeh, Nameer Aladamat, Mohammad Samara, Adam T Mierzwa, Ahsan Ali, Syed Zaidi, Mouhammad Jumaa

Open access · greenAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Acute ischemic stroke patient factors associated with poor outcomes in patients with favorable collaterals and successful thrombectomy.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Khaled GharaibehDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.ORCID 0000-0003-1800-9372
Nameer AladamatDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.
Mohammad SamaraDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.
Adam T MierzwaDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.
Ahsan AliDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.
Syed ZaidiDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.
Mouhammad JumaaDepartment of Neurology, University of Toledo College of Medicine, and Life Sciences, Toledo, OH, USA.
University of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveTo assess the prognostic values of hyperdense sign on pretreatment non-contrast head CT scan for successful recanalization (mTICI ≥2b) and 90-day good functional outcome (mRs 0-2) in patients with acute ischemic stroke undergoing mechanical thrombectomy (MT).MethodsLiterature search on PubMed, EMBASE, and Cochrane databases from inception up to 1 November 2023 was conducted. Twelve studies which reported hyperdense sign, recanalization and clinical outcomes were included in qualitative synthesis and meta-analysis.ResultsPooled analysis demonstrated a statistically significant association between successful recanalization and hyperdense sign-positive patients who underwent MT (odd ratios (OR) = 1.47, 95% confidence interval (CI) = 1.03-2.10,

Indexed as

Ischemic StrokeThrombectomyTomography, X-Ray ComputedHumansPrognosisTreatment Outcomehyperdesne vessel signStrokesuccessful recanalization

Identifiers

PMID38415302
PMCPMC11569727
OpenAlexW4392237871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.