Evidence map›Paper›PMID 38415034›Full record

ArticleBioinformation2023

Evaluation of immuno-histochemical markers in oral squamous cell carcinoma.

Yadavalli Guruprasad, Priya Singhal, Neha Gupta, Bhavna Jha Kukreja, Bharti Gupta, Pankaj Kukreja, Ramanpal Singh Makkad, Dhaval Niranjan Mehta

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yadavalli GuruprasadDepartment of Dentistry, Vijaynagar Institute of Medical Sciences, VIMS Campus, Cantonment, Ballari - 583104, India.
Priya SinghalSenior Resident, Department of Dentistry, SMS Medical College, Jaipur, India.
Neha GuptaDepartment of Oral Pathology, Microbiology and Forensic Odontology, Dental Institute, Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand, India.
Bhavna Jha KukrejaPeriodontology Preventive Dental sciences Department College of Dentistry, Gulf Medical University, Ajman UAE.
Bharti GuptaDepartment of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.
Pankaj KukrejaOral and Maxillofacial Surgery, Department of Biomedical and Dental Sciences, Faculty of Dentistry, Al Baha University, Al Aqiq Campus, Kingdom of Saudi Arabia.
Ramanpal Singh MakkadDepartment of Oral medicine and Radiology, New Horizon Dental College and Research, Institute, Sakri, Bilaspur, Chhattisgarh, India.
Dhaval Niranjan MehtaDepartment of Oral Medicine and Radiology, Narsinbhai Patel Dental college and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.
Vijayanagara Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluation of immuno-histochemical (IHC) markers like p53, p63, PDPN, C-erb-B2, CK19, and VEGF in oral squamous cell carcinoma (OSCCs) is of interest to dentists. Sixty formalin-fixed paraffin embedded tissue blocks from the Department of Oral Pathology, New Horizon Dental College and Research, Institute, Sakri, Bilaspur, Chhattisgarh, India. The conventional IHC method was used to assess the expression of p53, p63, PDPN, C- erb-B2, CK19 and VEGF using the different antibodies. Data shows that P53, p63 had high values of labeling index (LI) of staining while PDPN, C-erb-B2 had low values of LI of staining. The values of LI of staining for CK19, and VEGF were in between the two types of IHCs. Combining the analysis of multiple IHC markers for OSCC can yield precise cancer diagnosis results.

Indexed as

Immunohistochemistrymarkersoral squamous cell carcinoma

Identifiers

PMID38415034
PMCPMC10895524
OpenAlexW4391583181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.