Evidence map›Paper›PMID 38414991›Full record

ArticleRSC advances2024

Uric acid quantification

Umar Nishan, Ateeq Ahmed, Nawshad Muhammad, Mohibullah Shah, Muhammad Asad, Naeem Khan, Farman Ullah, Riaz Ullah, Essam A Ali, Haq Nawaz and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Umar NishanDepartment of Chemistry, Kohat University of Science and Technology Kohat 26000 KP Pakistan umarnishan85@gmail.com amirqau@yahoo.com.ORCID https://orcid.org/0000-0002-0106-3068
Ateeq AhmedDepartment of Chemistry, Kohat University of Science and Technology Kohat 26000 KP Pakistan umarnishan85@gmail.com amirqau@yahoo.com.
Nawshad MuhammadDepartment of Dental Materials, Institute of Basic Medical Sciences Khyber Medical University Peshawar KPK Pakistan.
Mohibullah ShahDepartment of Biochemistry, Bahauddin Zakariya University Multan 66000 Pakistan.
Muhammad AsadDepartment of Chemistry, Kohat University of Science and Technology Kohat 26000 KP Pakistan umarnishan85@gmail.com amirqau@yahoo.com.
Naeem KhanDepartment of Chemistry, Kohat University of Science and Technology Kohat 26000 KP Pakistan umarnishan85@gmail.com amirqau@yahoo.com.
Farman UllahDepartment of Pharmacy, Kohat University of Science and Technology Kohat 26000 KP Pakistan.
Riaz UllahDepartment of Pharmacognosy, College of Pharmacy, King Saud University Riyadh Saudi Arabia.
Essam A AliDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University Riyadh Saudi Arabia.
Haq NawazSchool of Chemistry and Chemical Engineering, Huaiyin Normal University 223300 Huaiyin Jiangsu China.
Amir BadshahDepartment of Chemistry, Kohat University of Science and Technology Kohat 26000 KP Pakistan umarnishan85@gmail.com amirqau@yahoo.com.
Kohat University of Science and Technology · PKKing Saud University · SABahauddin Zakariya University · PKHuaiyin Normal University · CNKhyber Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uric acid (UA) is a significant indicator of human health because it is linked to several diseases, including renal failure, kidney stones, arthritis, and gout. Uric acid buildup in the joints is the source of chronic and painful diseases. When UA is present in large quantities, it causes tissue injury in the joints that are afflicted. In this research, silver oxide-doped activated carbon nanoparticles were synthesized and then functionalized with an ionic liquid. The synthesized nanomaterial assembly was employed as a colorimetric sensing platform for uric acid. Activated carbon offers a large internal surface area that acts as a good carrier for catalytic reactions. A salt-melting approach was used to synthesize the silver oxide-doped activated carbon nanocomposite. The synthesis was confirmed through various techniques, such as UV-vis spectrophotometer, FTIR, XRD, SEM, and EDX. The colorimetric change from blue-green to colorless was observed with the naked eye and confirmed by UV-vis spectroscopy. To obtain the best colorimetric change, several parameters, such as pH, capped NP loading, TMB concentration, hydrogen peroxide concentration, and time, were optimized. The optimized experimental conditions for the proposed sensor were pH 4 with 35 μL of NPs, a 40 mM TMB concentration, and a 4 minutes incubation time. The sensor linear range is 0.001-0.36 μM, with an

Identifiers

PMID38414991
PMCPMC10898421
OpenAlexW4392206571

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.