Evidence map›Paper›PMID 38414850›Full record

ArticleiScience2024

When the heart inhibits the brain: Cardiac phases modulate short-interval intracortical inhibition.

Mario Paci, Pasquale Cardellicchio, Paolo Di Luzio, Mauro Gianni Perrucci, Francesca Ferri, Marcello Costantini

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. A cardiovascular-motor axis framework for perfusion-mediated motor impairment.International journal of cardiology. Heart & vasculature · 2026
    Review
  2. Article
  3. Moment-to-Moment Heart-Brain Interactions: How Cardiac Signals Influence Cortical Processing and Time Estimation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Cardiac signals inform auditory regularity processing in the absence of consciousness.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mario PaciDepartment of Neuroscience, Imaging and Clinical Science, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
Pasquale CardellicchioIIT@UniFe Center for Translational Neurophysiology, Istituto Italiano di Tecnologia, Via Fossato di Mortara, 17-19, 44121 Ferrara, Italy.
Paolo Di LuzioDepartment of Psychological, Health, and Territorial Sciences, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
Mauro Gianni PerrucciDepartment of Neuroscience, Imaging and Clinical Science, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
Francesca FerriDepartment of Neuroscience, Imaging and Clinical Science, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
Marcello CostantiniInstitute for Advanced Biomedical Technologies - ITAB, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phasic cardiovascular activity influences the central nervous system through the systolic baroreceptor inputs, inducing widespread inhibitory effects on behavior. Through transcranial magnetic stimulation (TMS) delivered during resting-state over the left primary motor cortex and across the different cardiac phases, we measured corticospinal excitability (CSE) and distinct indices of intracortical motor inhibition: short (SICI) and long (LICI) interval, corresponding to GABA

Indexed as

Biological sciencesClinical neuroscienceNatural sciencesNeuroscience

Identifiers

PMID38414850
PMCPMC10897847

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.