ArticleInternational journal of chronic obstructive pulmonary disease2024
Acute Exacerbation and Longitudinal Lung Function Change of Preserved Ratio Impaired Spirometry.
Article in International journal of chronic obstructive pulmonary disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Beyond spirometry: understanding COPD origins to support a new diagnostic approach.ERJ open research · 2026Review
- The risk factors of future exacerbations and treatment responses among different inhalation therapies of patients with preserved ratio impaired spirometry.Journal of global health · 2026Article
- Lung function trajectories and exacerbation risks in preserved ratio impaired spirometry (PRISm) patients.Scientific reports · 2026Article
- Article
- Associated Factors and Pulmonary Function Outcomes of Preserved Ratio Impaired Spirometry: A Scoping Review.International journal of chronic obstructive pulmonary disease · 2025Article
- Analysis of Endocrine and Inflammatory Markers in Preserved Ratio Impaired Spirometry.Medical sciences (Basel, Switzerland) · 2024Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Preserved ratio impaired spirometry (PRISm) is a heterogeneous disease entity. Limited data are available regarding its prevalence, clinical course, or prognosis. We aimed to evaluate the longitudinal clinical course of patients with PRISm compared with chronic obstructive pulmonary disease (COPD). Methods: A retrospective study enrolled PRISm and COPD patients who underwent chest computed tomography and longitudinal pulmonary function tests between January 2013 and December 2020. We compared the incidence of acute exacerbations and lung function changes between PRISm and COPD patients. Results: Of the 623 patients, 40 and 583 had PRISm and COPD, respectively. Compared to COPD patients, PRISm patients were younger, more likely to be female and have a history of tuberculosis, and less likely to be smokers. They also had less severe comorbidities, lower forced vital capacity (FVC) and diffusing capacity of the lungs for carbon monoxide (D Conclusion: PRISm patients had no significant difference in the risk of acute exacerbations, but a significantly slower decline of lung function during longitudinal follow-up, compared with COPD patients.
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Registered trials
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