Evidence map›Paper›PMID 38414681›Full record

ArticleCureus2024

Amyloid Light-Chain (AL) Amyloidosis of the Trachea Associated With an Indolent B-cell Neoplasm.

Anup Kumar Trikannad, Asis Shrestha, Sruthi Vellanki, Hira I Cheema, Tanvi H Patel, Ramya Bachu, Shobhit Sharma, Susanne K Jeffus, Sharmilan Thanendrarajan

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anup Kumar TrikannadInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Asis ShresthaInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Sruthi VellankiInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Hira I CheemaInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Tanvi H PatelInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Ramya BachuInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Shobhit SharmaRadiology, University of Arkansas for Medical Sciences, Little Rock, USA.
Susanne K JeffusPathology, University of Arkansas for Medical Sciences, Little Rock, USA.
Sharmilan ThanendrarajanHematology and Oncology, University of Arkansas for Medical Sciences, Little Rock, USA.
University of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 66-year-old woman who was diagnosed with localized tracheal amyloid light-chain (AL) amyloidosis caused by an underlying B-cell neoplasm. The diagnosis was confirmed through subsequent bronchoscopy and biopsies; however, she experienced a challenging episode of hypoxic respiratory failure that required intervention. Repeat bronchoscopies showed persistent subglottic stenosis and tracheobronchomalacia, which led to tracheal debulking surgery and additional interventions. The patient's treatment began with rituximab, zanubrutinib, and dexamethasone with outpatient follow-up. The rarity of tracheobronchial amyloidosis and its connection to B-cell malignancies are highlighted, emphasizing the challenges in diagnosis and the importance of tailored treatment strategies. The patient's clinical course, characterized by atypical respiratory symptoms, delayed diagnosis, and an evolving treatment approach, underscores the complexities of managing such a rare and intricate case.

Indexed as

amyloidosis (al)b cell neoplasmlocalized tracheal al amyloidosissmall cd5-positive monotypic b-cell populationtracheal stenosis

Identifiers

PMID38414681
PMCPMC10896678
OpenAlexW4391286076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.